Methyl 4,6-dichloropyridazine-3-carboxylate

Base Information

Chemical Name:Methyl 4,6-dichloropyridazine-3-carboxylate
CAS No.:372118-01-9
Molecular Formula:C6H4Cl2N2O2
Molecular Weight:207.016
Hs Code.:2933990090
European Community (EC) Number:810-083-2
DSSTox Substance ID:DTXSID30591259
Mol file:372118-01-9.mol

Synonyms:Methyl 4,6-dichloropyridazine-3-carboxylate;372118-01-9;4,6-DICHLORO-PYRIDAZINE-3-CARBOXYLIC ACID METHYL ESTER;MFCD09953612;3-methoxycarbonyl-4,6-dichloropyridazine;3-PYRIDAZINECARBOXYLIC ACID, 4,6-DICHLORO-, METHYL ESTER;SCHEMBL1343778;DTXSID30591259;MZEVRGMQXLNKEZ-UHFFFAOYSA-N;AMY22981;BCP28936;AKOS015919938;AB55529;CS-W008919;AC-27270;DA-32532;DS-12707;SY037593;methyl 4,6-dichloro-pyridazine-3-carboxylate;EN300-3256353;A874158;J-522280;4,6-dichloropyridazine-3-carboxylic acid methyl ester;Z1258932824

Suppliers and Price of Methyl 4,6-dichloropyridazine-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl4,6-dichloropyridazine-3-carboxylate
100mg
$ 65.00

SynQuest Laboratories
Methyl 4,6-dichloropyridazine-3-carboxylate 97%
250 mg
$ 71.00

SynQuest Laboratories
Methyl 4,6-dichloropyridazine-3-carboxylate 97%
5 g
$ 477.00

SynQuest Laboratories
Methyl 4,6-dichloropyridazine-3-carboxylate 97%
1 g
$ 141.00

Matrix Scientific
Methyl 4,6-dichloropyridazine-3-carboxylate 95+%
5g
$ 568.00

Matrix Scientific
Methyl 4,6-dichloropyridazine-3-carboxylate 95+%
500mg
$ 120.00

JR MediChem
Methyl4,6-Dichloropyridazine-3-carboxylate >96%
1g
$ 108.00

JR MediChem
Methyl4,6-Dichloropyridazine-3-carboxylate >96%
100g
$ 2980.00

J&W Pharmlab
4,6-Dichloro-pyridazine-3-carboxylicacidmethylester 96%
25g
$ 1380.00

J&W Pharmlab
4,6-Dichloro-pyridazine-3-carboxylicacidmethylester 96%
1g
$ 110.00

Total 72 raw suppliers

Chemical Property of Methyl 4,6-dichloropyridazine-3-carboxylate

Chemical Property:

Vapor Pressure:6.27E-05mmHg at 25°C
Refractive Index:1.552
Boiling Point:345.165 °C at 760 mmHg
PKA:-2.30±0.10(Predicted)
Flash Point:162.55 °C
PSA：52.08000
Density:1.504 g/cm³
LogP:1.57000
Storage Temp.:Inert atmosphere,Store in freezer, under -20°C
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:205.9649828
Heavy Atom Count:12
Complexity:179

Purity/Quality:

99%, ^*data from raw suppliers

Methyl4,6-dichloropyridazine-3-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=NN=C(C=C1Cl)Cl

Technology Process of Methyl 4,6-dichloropyridazine-3-carboxylate

There total 4 articles about Methyl 4,6-dichloropyridazine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 372118-00-8
4,6-dihydroxy-pyridazine-3-carboxylic acid methyl ester

: 372118-01-9
4,6-dichloro-pyridazine-3-carboxylic acid methyl ester

Guidance literature:: With trichlorophosphate; at 95 ℃; for 5h;

Reference yield:

: 1830-54-2
3-oxopentanedioic acid dimethyl ester

: 372118-01-9
4,6-dichloro-pyridazine-3-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine; 4-acetamidobenzenesulfonyl azide / acetonitrile / 1 h / 0 - 20 °C

2.1: triphenylphosphine / diethyl ether / 24 h / 20 °C

2.2: 10 h / Reflux

3.1: trichlorophosphate / 5 h / 95 °C

With 4-acetamidobenzenesulfonyl azide; triethylamine; triphenylphosphine; trichlorophosphate; In diethyl ether; acetonitrile;

Reference yield:

: 83878-89-1
2-diazo-3-oxo-pentanedioic acid dimethyl ester

: 372118-01-9
4,6-dichloro-pyridazine-3-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: triphenylphosphine / diethyl ether / 24 h / 20 °C

1.2: 10 h / Reflux

2.1: trichlorophosphate / 5 h / 95 °C

With triphenylphosphine; trichlorophosphate; In diethyl ether;