Benzyl 1-methylhydrazinecarboxylate

Base Information

• Chemical Name: Benzyl 1-methylhydrazinecarboxylate
• CAS No.: 37519-04-3
• Molecular Formula: C9H12N2O2
• Molecular Weight: 180.206
• Hs Code.: 2928000090
• European Community (EC) Number: 840-510-8
• DSSTox Substance ID: DTXSID00459019
• Nikkaji Number: J1.233.454K
• Wikidata: Q82282613
• Mol file: 37519-04-3.mol

Synonyms:Benzyl 1-methylhydrazinecarboxylate;37519-04-3;benzyl N-amino-N-methylcarbamate;Benzyl1-Methylhydrazinecarboxylate;Hydrazinecarboxylic acid, 1-methyl-, phenylmethyl ester;benzyl 2-methylcarbazate;1-Methylhydrazinecarboxylic acid phenylmethyl ester;SCHEMBL3149010;N-methyl(benzyloxy)carbohydrazide;DTXSID00459019;DHBHFHDKOHJROV-UHFFFAOYSA-N;2-Methylcarbazic acid benzyl ester;MFCD21604061;AKOS015999196;benzyl 1-methylhydrazine-1-carboxylate;CS-W022587;DS-16987;FT-0699470;EN300-133247;O11694;A856288

Chemical Property of Benzyl 1-methylhydrazinecarboxylate

Chemical Property:

• PSA: 55.56000
• LogP: 1.82900
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 180.089877630
• Heavy Atom Count: 13
• Complexity: 167

Purity/Quality:

97% ^*data from raw suppliers

Benzyl1-methylhydrazinecarboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C(=O)OCC1=CC=CC=C1)N

Technology Process of Benzyl 1-methylhydrazinecarboxylate

There total 13 articles about Benzyl 1-methylhydrazinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

N-methyl-N-benzyloxycarbonylaminophthalimide (287729-06-0) → 1-(benzyloxy)carbonyl-1-methylhydrazine (37519-04-3)

Guidance literature:

With methylhydrazine; In tetrahydrofuran; at 0 - 20 ℃;

DOI:10.1081/SCC-120014971

Reference yield: 88.0%

N-methyl-N-benzyloxycarbonylaminotetrachlorophthalimide → 1-(benzyloxy)carbonyl-1-methylhydrazine (37519-04-3)

Guidance literature:

With ethylenediamine; In tetrahydrofuran; at 0 - 20 ℃;

DOI:10.1081/SCC-120014971

Reference yield: 75.0%

N-(Benzyloxycarbonyloxy)succinimide (13139-17-8) + methylhydrazine (60-34-4) → 1-(benzyloxy)carbonyl-1-methylhydrazine (37519-04-3)

Guidance literature:

With 4-methyl-morpholine;

DOI:10.1016/0040-4039(95)02124-8

upstream raw materials:

benzyl chloroformate

methylhydrazine

DBC

N-(Benzyloxycarbonyloxy)succinimide

Downstream raw materials:

N¹-Benzyloxycarbonyl-N¹-methyl-N₂-(4-nitro-benzyliden)-hydrazin

N-t-butoxycarbonyl-L-alanyl-L-alanyl-α-aza-alanine benzyl ester

N-t-butoxycarbonyl-L-valylglycyl-α-aza-alanine benzyl ester

Boc-Val-Val-Azala-OBzl