2-(2-Aminophenethyl)-1-methylpiperidine

Base Information

Chemical Name:2-(2-Aminophenethyl)-1-methylpiperidine
CAS No.:37611-80-6
Molecular Formula:C14H22N2
Molecular Weight:218.342
Hs Code.:
DSSTox Substance ID:DTXSID101024442
Mol file:37611-80-6.mol

Synonyms:37611-80-6;2-(2-(1-Methylpiperidin-2-yl)ethyl)aniline;2-[2-(1-methylpiperidin-2-yl)ethyl]aniline;2-(2-aminophenethyl)-1-methylpiperidine;SCHEMBL659411;CCXFKJBMYLLRBW-UHFFFAOYSA-N;DTXSID101024442;2-(o-aminophenethyl)-1-methylpiperidine;2-(2-amino-phenethyl)-1-methylpiperidine;(+/-)-2-[2-(1-methyl-2-piperidinyl)ethyl]-benzenamine

Suppliers and Price of 2-(2-Aminophenethyl)-1-methylpiperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(2-Aminophenethyl)-1-methylpiperidine

Chemical Property:

Boiling Point:342.6±15.0 °C(Predicted)
PKA:9.95±0.10(Predicted)
PSA：29.26000
Density:1.001±0.06 g/cm3(Predicted)
LogP:3.20480
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:218.178298710
Heavy Atom Count:16
Complexity:205

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCCCC1CCC2=CC=CC=C2N

Technology Process of 2-(2-Aminophenethyl)-1-methylpiperidine

There total 5 articles about 2-(2-Aminophenethyl)-1-methylpiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 37611-80-6
2-(ortho-aminophenethyl)-1-methylpiperidine

Guidance literature:

Reference yield:

: 2-(2-nitrostyryl)-1-methylpyridinium methyl sulfate

: 37611-80-6
2-(ortho-aminophenethyl)-1-methylpiperidine

Guidance literature:: With hydrogen; platinum on activated charcoal; In ethanol; for 16h; under 103.4 Torr;
DOI:10.1002/jhet.5570300321

Reference yield:

: 2037-39-0
1,2-dimethylpyridinium methosulfate

: 37611-80-6
2-(ortho-aminophenethyl)-1-methylpiperidine

Guidance literature:: Multi-step reaction with 3 steps

1: piperidine / CH₂Cl₂ / 2 h

2: 96 percent / glac. AcOH, Ac₂O, KOAc / 2 h / Heating

3: hydrogen / Pt/C / aq. ethanol / 16 h / 103.4 Torr

With piperidine; hydrogen; potassium acetate; acetic anhydride; acetic acid; platinum on activated charcoal; In ethanol; dichloromethane;
DOI:10.1002/jhet.5570300321