anti-2-Acetoxyacetaldoxime

Base Information

• Chemical Name: anti-2-Acetoxyacetaldoxime
• CAS No.: 37858-07-4
• Molecular Formula: C₄H₇NO₃
• Molecular Weight: 117.104
• Mol file: 37858-07-4.mol

Synonyms:

Chemical Property of anti-2-Acetoxyacetaldoxime

Chemical Property:

• Melting Point: 35 °C(Solv: ethyl ether (60-29-7); ligroine (8032-32-4))
• Boiling Point: 115 °C(Press: 15 Torr)
• PKA: 8.49±0.10(Predicted)
• Density: 1.15±0.1 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Use Description: Anti-2-acetoxyacetaldoxime is a chemical compound with applications in various fields. In the field of organic chemistry, it serves as a versatile building block for the synthesis of diverse organic molecules. Its functional groups and reactivity make it valuable for creating compounds used in pharmaceuticals, agrochemicals, and specialty chemicals. Additionally, in the realm of chemical research and development, anti-2-Acetoxyacetaldoxime can be employed as a reagent or starting material for the development of new chemical reactions and methodologies, contributing to advancements in synthetic chemistry. Furthermore, in the pharmaceutical industry, it may play a role as an intermediate in the synthesis of specific drugs, underscoring its significance in drug discovery and development. Its adaptability as a chemical building block and research tool underscores its importance in advancing various aspects of chemistry, pharmaceuticals, and scientific research in different fields.

Technology Process of anti-2-Acetoxyacetaldoxime

There total 17 articles about anti-2-Acetoxyacetaldoxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

glyoxylic acid ethyl ester (924-44-7) → ethyl 2-(hydroxyimino)acetate (31767-14-3,31767-15-4,37858-07-4)

Guidance literature:

With hydroxylamine hydrochloride; triethylamine; In water; toluene; acetonitrile; at 20 ℃; for 1h;

DOI:10.1016/j.cbi.2018.10.022

Reference yield: 95.1%

chloral oxime (1117-99-3) → ethyl 2-(hydroxyimino)acetate (31767-14-3,31767-15-4,37858-07-4)

Guidance literature:

With sodium bicarbonate; In ethanol; water;

Reference yield: 90.0%

glyoxylic acid ethyl ester (924-44-7) + hydroxylamine (7803-49-8) → ethyl 2-(hydroxyimino)acetate (31767-14-3,31767-15-4,37858-07-4)

Guidance literature:

In toluene; at 20 ℃; for 2h; Molecular sieve;

upstream raw materials:

glyoxylic acid ethyl ester

ethyl 2-ethoxyglycolate

Carboethoxymethanenitronic acid methyl ester

ethyl acetoacetate

Downstream raw materials:

hydroxyimino-nitro-acetic acid ethyl ester

diethyl 1,2,5-oxadiazole-3,4-dicarboxylate 2-oxide

ethyl 2-chloro-2-(hydroxyimino)acetate

ethyl cyanoformate