Bis-coumaramidobutane

Base Information

Chemical Name:Bis-coumaramidobutane
CAS No.:37946-59-1
Molecular Formula:C22H24N2O4
Molecular Weight:380.444
Hs Code.:
UNII:HFN1DLN96K
DSSTox Substance ID:DTXSID70189932
Nikkaji Number:J1.528.101D,J3.509.184J
Wikidata:Q27279906
Metabolomics Workbench ID:46060
ChEMBL ID:CHEMBL4468096
Mol file:37946-59-1.mol

Synonyms:Bis-coumaramidobutane;Sid Corn DCP;N,N'-Dicoumaroylputrescine;364048-94-2;Di-4-coumaroylputrescine;UNII-HFN1DLN96K;HFN1DLN96K;CHEMBL4468096;2-Propenamide, N,N'-1,4-butanediylbis(3-(4-hydroxyphenyl)-, (2E,2'e)-;(E)-3-(4-hydroxyphenyl)-N-[4-[[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]amino]butyl]prop-2-enamide;37946-59-1;2-Propenamide, N,N'-1,4-butanediylbis[3-(4-hydroxyphenyl)-;N1,N4-Di-p-coumaroylputrescine;DTXSID70189932;CHEBI:175016;BIS-COUMARAMIDOBUTANE [INCI];BDBM50520912;AKOS040734981;J3.509.184J;N,N'-Bis(4-hydroxycinnamoyl)-1,4-butanediamine;N,N'-Tetramethylenebis(4-hydroxy-trans-cinnamamide);Q27279906;N,N'-(1,4-Butanediyl)bis[3-(4-hydroxyphenyl)propeneamide];N,N'-1,4-Butanediylbis[3-(4-hydroxyphenyl)-2-propenamide], 9CI;(2E)-3-(4-hydroxyphenyl)-N-{4-[(2E)-3-(4-hydroxyphenyl)prop-2-enamido]butyl}prop-2-enamide

Suppliers and Price of Bis-coumaramidobutane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Bis-coumaramidobutane

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:9
Exact Mass:380.17360725
Heavy Atom Count:28
Complexity:483

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1C=CC(=O)NCCCCNC(=O)C=CC2=CC=C(C=C2)O)O
Isomeric SMILES:C1=CC(=CC=C1/C=C/C(=O)NCCCCNC(=O)/C=C/C2=CC=C(C=C2)O)O

Technology Process of Bis-coumaramidobutane

There total 5 articles about Bis-coumaramidobutane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: N,N'-di(acetylcoumaroyl)putrescine

: 37946-59-1
N,N'-di-p-coumaroylputrescine

Guidance literature:: With potassium hydroxide; In water; at 50 ℃; for 0.5h;
DOI:10.5012/bkcs.2014.35.10.3085

Reference yield: 70.0%

: 7400-08-0,50940-26-6
para-coumaric acid

: 110-60-1
1,4-diaminobutane

: 37946-59-1
N,N'-di-p-coumaroylputrescine

Guidance literature:: With Fe³⁺ cation exchanged montmorillonite; In chloroform; for 4h; Reflux;
DOI:10.2174/157017811799304241

Reference yield:

: 7400-08-0,50940-26-6
para-coumaric acid

: 37946-59-1
N,N'-di-p-coumaroylputrescine

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine; dmap / tetrahydrofuran / 3 h / Reflux

2: thionyl chloride / 1 h / 0 °C / Reflux

3: triethylamine / dichloromethane / 2 h / 20 °C

4: potassium hydroxide / water / 0.5 h / 50 °C

With dmap; thionyl chloride; triethylamine; potassium hydroxide; In tetrahydrofuran; dichloromethane; water;
DOI:10.5012/bkcs.2014.35.10.3085