3-PHENYLISOQUINOLINE

Base Information

• Chemical Name: 3-PHENYLISOQUINOLINE
• CAS No.: 37993-76-3
• Molecular Formula: C15H11N
• Molecular Weight: 205.259
• Hs Code.: 2933499090
• Mol file: 37993-76-3.mol

Synonyms:3-PHENYLISOQUINOLINE;

Chemical Property of 3-PHENYLISOQUINOLINE

Chemical Property:

• Vapor Pressure: 4.38E-05mmHg at 25°C
• Melting Point: 100-105°C
• Boiling Point: 361.2±11.0 °C(Predicted)
• PKA: 4.52±0.30(Predicted)
• PSA: 12.89000
• Density: 1.127±0.06 g/cm3(Predicted)
• LogP: 3.90180

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-Phenylisoquinoline 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 22-24-38-41
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Uses: This material can be used as a ligand to synthesize a variety of OLED dopants.

Technology Process of 3-PHENYLISOQUINOLINE

There total 160 articles about 3-PHENYLISOQUINOLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(E)-tert-butyl({[2-(2-phenylethynyl)phenyl]methylidene})amine → 3-phenylisoquinoline (37993-76-3)

Guidance literature:

With copper(l) iodide; In N,N-dimethyl-formamide; at 100 ℃; for 3h;

DOI:10.1021/jo010579z DOI:10.1021/jo020020e

Reference yield: 98.0%

o-(phenylethynyl)benzaldehyde (59046-72-9) → 3-phenylisoquinoline (37993-76-3)

Guidance literature:

With silver hexafluoroantimonate; 4-methoxypyridine N-oxide; sodium tetrachloroaurate(III) dihyrate; ammonium acetate; In acetonitrile; at 85 ℃; for 2h; regioselective reaction; Sealed tube; Inert atmosphere;

DOI:10.1021/acs.joc.5b01939

Reference yield: 92.0%

phenylacetylene (536-74-3) + ortho-bromobenzaldehyde (6630-33-7) → 3-phenylisoquinoline (37993-76-3)

Guidance literature:

With copper(l) iodide; tert-butylamine; In N,N-dimethyl-formamide; at 140 ℃; for 0.0666667h; under 10501.1 Torr; Reagent/catalyst; Solvent; Microwave irradiation;

DOI:10.1039/c3ra46722h

upstream raw materials:

phthalimide

1-chloro-3-phenylisoquinoline

[2-(benzoylamino-methyl)-phenyl]-acetic acid

isoquinoline

Downstream raw materials:

2-methyl-3-phenyl-isoquinolinium; iodide

benzoyl(3-phenylisoquinolin-2-ium-2-yl)amide

1-chloro-3-phenylisoquinoline

N-[2-(isoquinolin-3-yl)phenyl]-4-methylbenzenesulfonamide