59046-72-9 Usage
Description
2-Phenylethynyl-benzaldehyde, an aromatic aldehyde with the molecular formula C16H12O, is a chemical compound known for its distinctive strong odor. It features a phenylethynyl group, which is a triple-bonded carbon chain attached to a benzene ring, contributing to its versatile reactivity. 2-PHENYLETHYNYL-BENZALDEHYDE is recognized for its potential as a precursor in the synthesis of pharmaceuticals, agrochemicals, and materials, as well as its applications in the development of organic electronic materials and as a fluorescent probe for sensing and imaging in biological and environmental systems.
Uses
Used in Organic Chemical Synthesis:
2-Phenylethynyl-benzaldehyde is used as a building block in organic chemical synthesis for its versatile reactivity, allowing for the creation of a wide range of compounds with various applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-phenylethynyl-benzaldehyde is used as a precursor for the production of various pharmaceuticals, leveraging its reactivity to form new medicinal compounds.
Used in Agrochemical Industry:
Similarly, in the agrochemical industry, this compound serves as a precursor, contributing to the development of new agrochemical products.
Used in Material Science:
2-Phenylethynyl-benzaldehyde is utilized in material science for the development of new materials, taking advantage of its structural properties to enhance material performance.
Used in Organic Electronic Materials:
2-PHENYLETHYNYL-BENZALDEHYDE is also used in the research and development of organic electronic materials, where its unique properties can contribute to the performance of organic electronic devices.
Used as a Fluorescent Probe in Biological and Environmental Systems:
2-Phenylethynyl-benzaldehyde is employed as a fluorescent probe for sensing and imaging applications in biological and environmental systems, capitalizing on its fluorescent properties to detect and monitor various processes or substances.
Check Digit Verification of cas no
The CAS Registry Mumber 59046-72-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,0,4 and 6 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 59046-72:
(7*5)+(6*9)+(5*0)+(4*4)+(3*6)+(2*7)+(1*2)=139
139 % 10 = 9
So 59046-72-9 is a valid CAS Registry Number.
InChI:InChI=1/C15H10O/c16-12-15-9-5-4-8-14(15)11-10-13-6-2-1-3-7-13/h1-9,12H
59046-72-9Relevant articles and documents
Catalytic Asymmetric Tandem Reaction of o-Alkynylbenzaldehydes, Amines, and Diazo Compounds
Wu, Wei,Liao, Na,Wei, Qi,Huang, Jiaying,Huang, Qi,Peng, Yungui
supporting information, p. 6872 - 6876 (2021/09/14)
An efficient asymmetric tandem reaction of o-alkynylbenzaldehydes, amines, and diazo compounds catalyzed by chiral silver imidodiphosphate has been established. Chiral 1,2-dihydroisoquinoline analogues have a tertiary stereocenter at the C1 position, and substituents at the C3 position are available with up to 97% yields and 98% ee. These products can be elaborated into the corresponding β-aminophosphonates or PARP1-inhibitor analogues.
Facile preparation of 3-aryl-4-iodoisoquinolines from N-(o-Arylethynyl)benzyl p-toluenesulfonamides with iodine and base
Naruto, Hiroki,Togo, Hideo
, (2021/02/20)
Treatment of N-(o-arylethynyl)benzyl p-toluenesulfonamides with molecular iodine in the presence of NaHCO3 at 60 °C, followed by the reaction with tBuOK at room temperature gave 3-aryl-4-iodoisoquinolines in good yields. 4-Iodo-3-phenylisoquinoline, which is one of the obtained 3-aryl-4-iodoisoquinolines, was further transformed into isoquinoline derivatives smoothly. The present approach is a novel one-pot method for the preparation of 3-aryl-4-iodoisoquinolines from N-(o-arylethynyl)benzyl p-toluenesulfonamides under transition-metal-free conditions.
Palladium-Catalyzed Aminomethylative Oppolzer-Type Cyclization of Enynes: Access to Aminomethylated Benzofulvenes
Huang, Hanmin,Huang, Renbin,Li, Renren,Yu, Bangkui
supporting information, p. 9510 - 9515 (2021/12/14)
A novel palladium-catalyzed Oppolzer-type cyclization reaction aided by the aminomethyl cyclopalladated complex has been developed, which provides rapid access to functionalized benzofulvenes with excellent stereoselectivity. The corresponding products can undergo Diels–Alder reaction with maleimides, providing a series of complex polycyclic compounds with excellent regio- and stereoselectivities.
