3-Pyridinol, 2-[[(2-hydroxyphenyl)methylene]amino]-

Base Information

• Chemical Name: 3-Pyridinol, 2-[[(2-hydroxyphenyl)methylene]amino]-
• CAS No.: 38016-39-6
• Molecular Formula: C₁₂H₁₀N₂O₂
• Molecular Weight: 214.224
• Mol file: 38016-39-6.mol

Synonyms:2-[[(2-hydroxyphenyl)methylidene]amino]pyridin-3-ol;3-Pyridinol,2-[[(2-hydroxyphenyl)methylene]amino];2-[(2-hydroxybenzylidene)amino]pyridin-3-ol;

Chemical Property of 3-Pyridinol, 2-[[(2-hydroxyphenyl)methylene]amino]-

Chemical Property:

• Melting Point: 130 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7))
• Boiling Point: 524.5±45.0 °C(Predicted)
• PSA: 62.22000
• Density: 1.24±0.1 g/cm3(Predicted)
• LogP: 1.85110

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Pyridinol, 2-[[(2-hydroxyphenyl)methylene]amino]-

There total 2 articles about 3-Pyridinol, 2-[[(2-hydroxyphenyl)methylene]amino]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2-amino-3-hydroxypyridine (16867-03-1) + salicylaldehyde (90-02-8) → 2-[[(2-hydroxyphenyl)methylidene]amino]pyridin-3-ol (137838-24-5,38016-39-6)

Guidance literature:

In ethanol; at 60 ℃; Reflux;

DOI:10.1016/j.saa.2010.03.026

Reference yield:

→ 2-[[(2-hydroxyphenyl)methylidene]amino]pyridin-3-ol (137838-24-5,38016-39-6)

Guidance literature:

entspr. 3-Hydroxypyridinverb., entspr. Aldehyd;

Reference yield:

uranyl(VI) acetate dihydrate + 2-[[(2-hydroxyphenyl)methylidene]amino]pyridin-3-ol (137838-24-5,38016-39-6) → 2O(C5H3N)NCH(C6H4)OH(1-)*UO2(2+)*4H2O=(C12H9N2O2)2UO2*4H2O

Guidance literature:

In ethanol; reflux, 1 h; filtration, washing with abs. ethanol, drying over silica gel; elem. anal.;

upstream raw materials:

2-amino-3-hydroxypyridine

salicylaldehyde