Methyl 5-phenyloxazole-4-carboxylate ,97%

Base Information

• Chemical Name: Methyl 5-phenyloxazole-4-carboxylate ,97%
• CAS No.: 38061-18-6
• Molecular Formula: C11H9NO3
• Molecular Weight: 203.197
• Hs Code.: 29349990
• Mol file: 38061-18-6.mol

Synonyms:methyl 5-phenyl-4-oxazolecarboxylate;5-phenyl-oxazole-4-carboxylic acid methyl ester;methyl 5-phenyloxazole-4-carboxylate;5-PHENYLFURAN-2-CARBOXYLIC ACID METHYL ESTER;methyl 5-phenyl-2-furonate;2-Furancarboxylic acid,5-phenyl-,methyl ester;methyl 5-phenyl-2-furoate;5-Ph-oxazol-4-carbonsaeure-Me-ester;5-Phenyloxazol-4-carbonsaeuremethylester;4-methoxycarbonyl-5-phenyloxazole;

Chemical Property of Methyl 5-phenyloxazole-4-carboxylate ,97%

Chemical Property:

• PSA: 52.33000
• LogP: 2.12820

Purity/Quality:

97% ^*data from raw suppliers

Methyl5-phenyloxazole-4-carboxylate 97% ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl 5-phenyloxazole-4-carboxylate ,97%

There total 7 articles about Methyl 5-phenyloxazole-4-carboxylate ,97% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

isocyanoacetic acid methyl ester (39687-95-1) + benzoic acid anhydride (93-97-0) → methyl 5-phenyl-4-oxazolecarboxylate (38061-18-6)

Guidance literature:

With P(MeNCH₂CH₂)3N; In tetrahydrofuran; 1.) 5 deg C, 15 min, 2.) r.t., 30 min;

DOI:10.1021/jo00104a041

Reference yield: 95.0%

benzoic acid phenyl ester (93-99-2) + isocyanoacetic acid methyl ester (39687-95-1) → methyl 5-phenyl-4-oxazolecarboxylate (38061-18-6)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 - 24 ℃; for 24h;

DOI:10.1002/anie.201402788

Reference yield: 84.0%

isocyanoacetic acid methyl ester (39687-95-1) + phenylglyoxylic acid potassium salt (63468-90-6) → methyl 5-phenyl-4-oxazolecarboxylate (38061-18-6)

Guidance literature:

With dipotassium peroxodisulfate; 1,10-Phenanthroline; silver carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 12h; Reagent/catalyst; Solvent; Catalytic behavior; Kinetics; Schlenk technique; Inert atmosphere;

DOI:10.1039/c5cc02253c

upstream raw materials:

isocyanoacetic acid methyl ester

benzoyl chloride

benzoic acid anhydride

benzoic acid

Downstream raw materials:

α-Phenylacyl amino acid methyl ester hydrochloride

5-phenyl-1,3-oxazole-4-carboxylic acid

methyl 2-benzoyl-5-phenyloxazole-4-carboxylate

2-Aminoacetophenone