2-Hydroxynaphthalene-1-carbonyl chloride

Base Information

Chemical Name:2-Hydroxynaphthalene-1-carbonyl chloride
CAS No.:38077-75-7
Molecular Formula:C11H7ClO2
Molecular Weight:206.62500
Hs Code.:
DSSTox Substance ID:DTXSID60700079
Wikidata:Q82631261
Mol file:38077-75-7.mol

Synonyms:38077-75-7;2-HYDROXYNAPHTHALENE-1-CARBONYL CHLORIDE;8-Naphthol-1-boronic acid;1-NAPHTHALENECARBONYL CHLORIDE,2-HYDROXY-;Diphenylaceticacid;SCHEMBL3918323;DTXSID60700079;FT-0732712

Suppliers and Price of 2-Hydroxynaphthalene-1-carbonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
1-NAPHTHALENECARBONYLCHLORIDE,2-HYDROXY- 95
50g
$ 2475.00

American Custom Chemicals Corporation
1-NAPHTHALENECARBONYL CHLORIDE,2-HYDROXY- 95.00%
5MG
$ 505.89

Alichem
8-Naphthol-1-boronicacid
250mg
$ 801.49

Total 6 raw suppliers

Chemical Property of 2-Hydroxynaphthalene-1-carbonyl chloride

Chemical Property:

PSA：37.30000
LogP:2.92440
XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:206.0134572
Heavy Atom Count:14
Complexity:229

Purity/Quality:

98%min ^*data from raw suppliers

1-NAPHTHALENECARBONYLCHLORIDE,2-HYDROXY- 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=CC(=C2C(=O)Cl)O

Technology Process of 2-Hydroxynaphthalene-1-carbonyl chloride

There total 3 articles about 2-Hydroxynaphthalene-1-carbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2283-08-1
2-hydroxy-1-naphthalenecarboxylic acid

: 38077-75-7
2-Hydroxy-naphthalene-1-carbonyl chloride

Guidance literature:: With thionyl chloride; N,N-dimethyl-formamide; In n-heptane; at 60 ℃;
DOI:10.1016/j.bmc.2004.07.062

Reference yield:

: 2-hydroxy-1-naphthoic acid sodium salt

: 38077-75-7
2-Hydroxy-naphthalene-1-carbonyl chloride

Guidance literature:: With oxalyl dichloride; In dichloromethane; at 25 ℃; for 0.5h;

Reference yield:

: 947-65-9
methyl 2-hydroxy-1-naphthoate

: 38077-75-7
2-Hydroxy-naphthalene-1-carbonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / water; methanol / 12 h / 60 °C / Inert atmosphere

2: thionyl chloride / toluene / 6 h / 80 °C / Inert atmosphere

With thionyl chloride; sodium hydroxide; In methanol; water; toluene;
DOI:10.1021/acs.orglett.9b02604