1-Piperidinecarboxylic acid, 4-[[[[[(2,4-dimethoxyphenyl)methyl](4-methoxybenzoyl)amino][2-(trifluoro methyl)phenyl]acetyl]amino]methyl]-, 1,1-dimethylethyl ester

Base Information

Chemical Name:1-Piperidinecarboxylic acid, 4-[[[[[(2,4-dimethoxyphenyl)methyl](4-methoxybenzoyl)amino][2-(trifluoro methyl)phenyl]acetyl]amino]methyl]-, 1,1-dimethylethyl ester
CAS No.:380901-85-9
Molecular Formula:C₃₇H₄₄F₃N₃O₇
Molecular Weight:699.767
Hs Code.:

1-Piperidinecarboxylic acid,
4-[[[[[(2,4-dimethoxyphenyl)methyl](4-methoxybenzoyl)amino][2-(trifluoro
methyl)phenyl]acetyl]amino]methyl]-, 1,1-dimethylethyl ester

Synonyms:

Suppliers and Price of 1-Piperidinecarboxylic acid, 4-[[[[[(2,4-dimethoxyphenyl)methyl](4-methoxybenzoyl)amino][2-(trifluoro methyl)phenyl]acetyl]amino]methyl]-, 1,1-dimethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-Piperidinecarboxylic acid, 4-[[[[[(2,4-dimethoxyphenyl)methyl](4-methoxybenzoyl)amino][2-(trifluoro methyl)phenyl]acetyl]amino]methyl]-, 1,1-dimethylethyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Hazard Codes:

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Useful:

Technology Process of 1-Piperidinecarboxylic acid, 4-[[[[[(2,4-dimethoxyphenyl)methyl](4-methoxybenzoyl)amino][2-(trifluoro methyl)phenyl]acetyl]amino]methyl]-, 1,1-dimethylethyl ester

There total 4 articles about 1-Piperidinecarboxylic acid, 4-[[[[[(2,4-dimethoxyphenyl)methyl](4-methoxybenzoyl)amino][2-(trifluoro methyl)phenyl]acetyl]amino]methyl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 144222-22-0
tert-butyl 4-(aminomethyl)piperidine-1-carboxylate

: 380901-85-9
4-{[2-[(2,4-dimethoxy-benzyl)-(4-methoxy-benzoyl)-amino]-2-(2-trifluoromethyl-phenyl)-acetylamino]-methyl}-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 35 percent / aq. NaOH; Bn(Et)3NCl / CH₂Cl₂ / 1.5 h / Heating

2: methanol / 20 °C

With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In methanol; dichloromethane;
DOI:10.1016/S0960-894X(03)00462-1

Reference yield:

: 100-09-4
4-methoxybenzoic acid

: 380901-64-4
4-isocyanomethyl-piperidine-1-carboxylic acid tert-butyl ester

: (2,4-Dimethoxy-benzyl)-[1-(2-trifluoromethyl-phenyl)-meth-(Z)-ylidene]-amine

: 380901-85-9
4-{[2-[(2,4-dimethoxy-benzyl)-(4-methoxy-benzoyl)-amino]-2-(2-trifluoromethyl-phenyl)-acetylamino]-methyl}-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: In methanol; at 20 ℃;
DOI:10.1016/S0960-894X(03)00462-1

Reference yield:

: 447-61-0
2-Trifluoromethylbenzaldehyde

: 380901-85-9
4-{[2-[(2,4-dimethoxy-benzyl)-(4-methoxy-benzoyl)-amino]-2-(2-trifluoromethyl-phenyl)-acetylamino]-methyl}-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / 20 °C

2: methanol / 20 °C

In methanol;
DOI:10.1016/S0960-894X(03)00462-1