1-Piperidinecarboxylic acid, 4-[[[[[(2,4-dimethoxyphenyl)methyl](4-methoxybenzoyl)amino](2-phenoxy phenyl)acetyl]amino]methyl]-, 1,1-dimethylethyl ester

Base Information

Chemical Name:1-Piperidinecarboxylic acid, 4-[[[[[(2,4-dimethoxyphenyl)methyl](4-methoxybenzoyl)amino](2-phenoxy phenyl)acetyl]amino]methyl]-, 1,1-dimethylethyl ester
CAS No.:380901-97-3
Molecular Formula:C₄₂H₄₉N₃O₈
Molecular Weight:723.866
Hs Code.:

1-Piperidinecarboxylic acid,
4-[[[[[(2,4-dimethoxyphenyl)methyl](4-methoxybenzoyl)amino](2-phenoxy
phenyl)acetyl]amino]methyl]-, 1,1-dimethylethyl ester

Synonyms:

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Chemical Property of 1-Piperidinecarboxylic acid, 4-[[[[[(2,4-dimethoxyphenyl)methyl](4-methoxybenzoyl)amino](2-phenoxy phenyl)acetyl]amino]methyl]-, 1,1-dimethylethyl ester

Chemical Property:

Purity/Quality:

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Technology Process of 1-Piperidinecarboxylic acid, 4-[[[[[(2,4-dimethoxyphenyl)methyl](4-methoxybenzoyl)amino](2-phenoxy phenyl)acetyl]amino]methyl]-, 1,1-dimethylethyl ester

There total 4 articles about 1-Piperidinecarboxylic acid, 4-[[[[[(2,4-dimethoxyphenyl)methyl](4-methoxybenzoyl)amino](2-phenoxy phenyl)acetyl]amino]methyl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 144222-22-0
tert-butyl 4-(aminomethyl)piperidine-1-carboxylate

: 380901-97-3
4-{[2-[(2,4-dimethoxy-benzyl)-(4-methoxy-benzoyl)-amino]-2-(2-phenoxy-phenyl)-acetylamino]-methyl}-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 35 percent / aq. NaOH; Bn(Et)3NCl / CH₂Cl₂ / 1.5 h / Heating

2: methanol / 20 °C

With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In methanol; dichloromethane;
DOI:10.1016/S0960-894X(03)00462-1

Reference yield:

: 100-09-4
4-methoxybenzoic acid

: 380901-64-4
4-isocyanomethyl-piperidine-1-carboxylic acid tert-butyl ester

: (2,4-Dimethoxy-benzyl)-[1-(2-phenoxy-phenyl)-meth-(Z)-ylidene]-amine

: 380901-97-3
4-{[2-[(2,4-dimethoxy-benzyl)-(4-methoxy-benzoyl)-amino]-2-(2-phenoxy-phenyl)-acetylamino]-methyl}-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: In methanol; at 20 ℃;
DOI:10.1016/S0960-894X(03)00462-1

Reference yield:

: 20781-20-8
2,4-Dimethoxybenzylamine

: 380901-97-3
4-{[2-[(2,4-dimethoxy-benzyl)-(4-methoxy-benzoyl)-amino]-2-(2-phenoxy-phenyl)-acetylamino]-methyl}-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / 20 °C

2: methanol / 20 °C

In methanol;
DOI:10.1016/S0960-894X(03)00462-1