1-Piperidinecarboxylic acid, 4-[[[[[(2,4-dimethoxyphenyl)methyl](4-methoxybenzoyl)amino][2-(phenyl methoxy)phenyl]acetyl]amino]methyl]-, 1,1-dimethylethyl ester

Base Information

Chemical Name:1-Piperidinecarboxylic acid, 4-[[[[[(2,4-dimethoxyphenyl)methyl](4-methoxybenzoyl)amino][2-(phenyl methoxy)phenyl]acetyl]amino]methyl]-, 1,1-dimethylethyl ester
CAS No.:380902-01-2
Molecular Formula:C43H51N3O8
Molecular Weight:737.893
Hs Code.:

1-Piperidinecarboxylic acid,
4-[[[[[(2,4-dimethoxyphenyl)methyl](4-methoxybenzoyl)amino][2-(phenyl
methoxy)phenyl]acetyl]amino]methyl]-, 1,1-dimethylethyl ester

Synonyms:

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Chemical Property of 1-Piperidinecarboxylic acid, 4-[[[[[(2,4-dimethoxyphenyl)methyl](4-methoxybenzoyl)amino][2-(phenyl methoxy)phenyl]acetyl]amino]methyl]-, 1,1-dimethylethyl ester

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Technology Process of 1-Piperidinecarboxylic acid, 4-[[[[[(2,4-dimethoxyphenyl)methyl](4-methoxybenzoyl)amino][2-(phenyl methoxy)phenyl]acetyl]amino]methyl]-, 1,1-dimethylethyl ester

There total 3 articles about 1-Piperidinecarboxylic acid, 4-[[[[[(2,4-dimethoxyphenyl)methyl](4-methoxybenzoyl)amino][2-(phenyl methoxy)phenyl]acetyl]amino]methyl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 144222-22-0
tert-butyl 4-(aminomethyl)piperidine-1-carboxylate

: 380902-01-2
4-({2-(2-benzyloxy-phenyl)-2-[(2,4-dimethoxy-benzyl)-(4-methoxy-benzoyl)-amino]-acetylamino}-methyl)-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 35 percent / aq. NaOH; Bn(Et)3NCl / CH₂Cl₂ / 1.5 h / Heating

2: methanol / 20 °C

With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In methanol; dichloromethane;
DOI:10.1016/S0960-894X(03)00462-1

Reference yield:

: 20781-20-8
2,4-Dimethoxybenzylamine

: 380902-01-2
4-({2-(2-benzyloxy-phenyl)-2-[(2,4-dimethoxy-benzyl)-(4-methoxy-benzoyl)-amino]-acetylamino}-methyl)-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / 20 °C

2: methanol / 20 °C

In methanol;
DOI:10.1016/S0960-894X(03)00462-1

Reference yield:

: 5896-17-3
2-(phenylmethoxy)benzaldehyde

: 380902-01-2
4-({2-(2-benzyloxy-phenyl)-2-[(2,4-dimethoxy-benzyl)-(4-methoxy-benzoyl)-amino]-acetylamino}-methyl)-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / 20 °C

2: methanol / 20 °C

In methanol;
DOI:10.1016/S0960-894X(03)00462-1