N-Hydroxy-3-(trifluoromethyl)aniline

Base Information

Chemical Name:N-Hydroxy-3-(trifluoromethyl)aniline
CAS No.:38160-76-8
Molecular Formula:C7H6F3NO
Molecular Weight:177.126
Hs Code.:
DSSTox Substance ID:DTXSID60523169
Nikkaji Number:J2.211.091H
Wikidata:Q82389101
Mol file:38160-76-8.mol

Synonyms:38160-76-8;N-Hydroxy-3-(trifluoromethyl)aniline;N-[3-(Trifluoromethyl)phenyl]hydroxylamine;Benzenamine, N-hydroxy-3-(trifluoromethyl)-;SCHEMBL8097513;DTXSID60523169;BTBCKFKJZWXNSB-UHFFFAOYSA-N

Suppliers and Price of N-Hydroxy-3-(trifluoromethyl)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-Hydroxy-3-(trifluoromethyl)aniline

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:177.04014830
Heavy Atom Count:12
Complexity:148

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)NO)C(F)(F)F

Technology Process of N-Hydroxy-3-(trifluoromethyl)aniline

There total 4 articles about N-Hydroxy-3-(trifluoromethyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 98-46-4
3-trifluoromethylnitrobenzene

: 38160-76-8
N-<3-(α,α,α-Trifluoromethyl)phenyl>hydroxylamine

Guidance literature:: With 5% Rh/C; hydrazine hydrate; In tetrahydrofuran; at 0 ℃; Inert atmosphere; Schlenk technique; Sealed tube;
DOI:10.1002/anie.201803026

Reference yield: 38.0%

: 98-46-4
3-trifluoromethylnitrobenzene

: 98-16-8
3-trifluoromethylaniline

: 38160-76-8
N-<3-(α,α,α-Trifluoromethyl)phenyl>hydroxylamine

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; hydrogen; palladium on activated charcoal;
DOI:10.1016/j.tetlet.2005.10.165

Reference yield:

: 6480-64-4
3-nitroso-1-(trifluoromethyl)benzene

: 38160-76-8
N-<3-(α,α,α-Trifluoromethyl)phenyl>hydroxylamine

Guidance literature:: With 1-Benzyl-3,5-bis(1-pyrrolidinylcarbonyl)-1,4-dihydropyridine; cobalt(II) perchlorate; In acetonitrile; at 25 ℃; for 0.25h; Rate constant; various metal catalysts;
DOI:10.1246/bcsj.60.1887