1-BROMO-4-CYCLOPROPOXY-BENZENE

Base Information

• Chemical Name: 1-BROMO-4-CYCLOPROPOXY-BENZENE
• CAS No.: 38380-85-7
• Molecular Formula: C9H9BrO
• Molecular Weight: 213.074
• Hs Code.: 2909309090
• Mol file: 38380-85-7.mol

Synonyms:1-bromo-4-(cyclopropoxy)benzene;1-bromo-4-(cyclopropyloxy)benzene;

Chemical Property of 1-BROMO-4-CYCLOPROPOXY-BENZENE

Chemical Property:

• Boiling Point: 259.9±13.0 °C(Predicted)
• PSA: 9.23000
• Density: 1.533±0.06 g/cm3(Predicted)
• LogP: 2.99030
• Storage Temp.: Room temperature.

Purity/Quality:

98.5% ^*data from raw suppliers

1-Bromo-4-cyclopropoxybenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-BROMO-4-CYCLOPROPOXY-BENZENE

There total 9 articles about 1-BROMO-4-CYCLOPROPOXY-BENZENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-bromophenyl vinyl ether (1005-61-4) + Chloroiodomethane (593-71-5) → 1-bromo-4-(cyclopropyloxy)benzene (38380-85-7)

Guidance literature:

With diethylzinc; In n-heptane; 1,2-dichloro-ethane; at 0 - 5 ℃; for 3h;

Reference yield: 72.0%

4-bromophenyl vinyl ether (1005-61-4) + diiodomethane (75-11-6) → 1-bromo-4-(cyclopropyloxy)benzene (38380-85-7)

Guidance literature:

4-bromophenyl vinyl ether; diiodomethane; With diethylzinc; In hexane; 1,2-dichloro-ethane; at 0 - 20 ℃; for 64.5h;

With water; ammonium chloride; In hexane; 1,2-dichloro-ethane;

Reference yield: 54.0%

4-bromo-phenol (106-41-2) + potassium cyclopropyltrifluoroborate (1065010-87-8) → 1-bromo-4-(cyclopropyloxy)benzene (38380-85-7)

Guidance literature:

With 1,10-Phenanthroline; oxygen; copper diacetate; potassium carbonate; In water; toluene; at 70 ℃; for 12h; under 760.051 Torr;

DOI:10.1021/acs.joc.7b03100

upstream raw materials:

4-bromophenyl vinyl ether

diethylzinc

Chloroiodomethane

diiodomethane

Downstream raw materials:

(4-cyclopropoxyphenyl)boronic acid

(4-cyclopropoxyphenylethynyl)trimethylsilane

4-(cyclopropyloxy)benzoic acid

4-cyclopropoxybenzoyl chloride