1005-61-4

Usage

Uses

Used in Pharmaceutical Industry:
1-Bromo-4-(ethenyloxy)benzene is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its reactivity in organic synthesis aids in the formation of carbon-carbon bonds, which are crucial for creating complex molecular structures in drug development.
Used in Agrochemical Industry:
In the agrochemical industry, 1-Bromo-4-(ethenyloxy)benzene is utilized as an intermediate in the production of agrochemicals. Its role in creating carbon-carbon bonds is essential for developing compounds that can be used in pesticides, herbicides, and other agricultural applications.
Used in Dye Manufacturing:
1-Bromo-4-(ethenyloxy)benzene is used as a building block in the manufacture of dyes. Its structural properties contribute to the development of dyes with specific color characteristics and stability.
Used in Perfumery:
1-BroMo-4-(ethenyloxy)benzene is also used in the production of perfumes, where its chemical structure plays a role in creating unique and complex fragrances.
Used in Flavorings Production:
1-Bromo-4-(ethenyloxy)benzene contributes to the development of flavorings, where its chemical properties can be manipulated to produce specific tastes and aromas in food and beverage industries.

Upstream product

• 106-41-2 4-bromo-phenol 
• 106-93-4 ethylene dibromide 
• 74-85-1 ethene 
• 75-20-7 calcium carbide 
• 108-05-4 vinyl acetate 
• 55162-34-0 1-bromo-4-(2-chloroethoxy)benzene 
• 1112-56-7 tetravinyltin (IV) 
• 18800-30-1 1-bromo-4-(2-bromoethoxy)benzene 

Downstream Products

• 34573-92-7 1,1,2,2-Tetracyano-3-(4'-bromo)-phenoxycyclobutan 
• 111862-30-7 1-Bromo-4-(1-chloro-2-thiocyanato-ethoxy)-benzene 
• 111862-24-9 1-(1,2-Bis-thiocyanato-ethoxy)-4-bromo-benzene 
• 34649-15-5 4-(vinyloxy)-benzonitrile 
• 117951-07-2 2-(4-Bromo-phenoxy)-2-chloro-ethanesulfonyl fluoride 
• 128997-93-3 1-[(4R,6S)-4,6-Bis-(4-bromo-phenoxy)-2-trifluoromethyl-5,6-dihydro-4H-pyran-3-yl]-2,2,2-trifluoro-ethanone 
• 128997-93-3 1-[(4R,6R)-4,6-Bis-(4-bromo-phenoxy)-2-trifluoromethyl-5,6-dihydro-4H-pyran-3-yl]-2,2,2-trifluoro-ethanone 
• 63053-32-7 β-Phenylsulfonyl-α-chlorethyl-p-bromphenylether 
• 38380-85-7 1-bromo-4-(cyclopropyloxy)benzene 
• 137711-39-8 (E)-2-(4-Bromo-phenoxy)-ethenesulfonyl fluoride 
• 111862-36-3 1-Bromo-4-((E)-2-thiocyanato-vinyloxy)-benzene 
• 62577-90-6 4-(cyclopropyloxy)benzoic acid 
• 1005487-45-5 4-cyclopropoxybenzoyl chloride 
• 1310817-14-1 1-[[4-(cyclopropoxy)benzoyl]amino]cyclopropanecarboxylic acid 

Relevant academic research and scientific papers

Spin Delocalization, Polarization, and London Dispersion Forces Govern the Formation of Diradical Pimers

Some free radicals are stable enough to be isolated, but most are either unstable transient species or exist as metastable species in equilibrium with a dimeric form, usually a spin-paired sigma dimer or a pi dimer (pimer). To gain insight into the different modes of dimerization, we synthesized and evaluated a library of 15 aryl dicyanomethyl radicals in order to probe what structural and molecular parameters lead to σ- versus π-dimerization. We evaluated the divergent dimerization behavior by measuring the strength of each radical association by variableerature electron paramagnetic resonance spectroscopy, determining the mode of dimerization (σ- or π-dimer) by UV-vis spectroscopy and X-ray crystallography, and performing computational analysis. We evaluated three different hypotheses to explain the difference in the dimerization behavior: (1) that the dimerization behavior is dictated by radical spin densities; (2) that it is dictated by radical polarizability; (3) that it is dictated by London dispersion stabilization of the pimer. However, no single parameter model in itself was predictive. Two-parameter models incorporating either the computed degree of spin delocalization or the radical polarizability as well as computed estimates for the attractive London dispersion forces in the π-dimers lead to improved forecasts of σ- vs π-dimerization mode, and suggest that a balance of spin delocalization of the isolated radical as well as attractive forces between the stacked radicals, govern the formation of diradical pimers.

HYDROXY ISOXAZOLE COMPOUNDS USEFUL AS GPR120 AGONISTS

The present invention relates to a compound represented by formula (I) : and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing diabetes, hyperlipidemia, obesity, NASH, inflammation related disorders, and related diseases and conditions. The compounds are useful as agonists of the G-protein coupled receptor GPR120. Pharmaceutical compositions and methods of treatment are also included.

Direct vinylation of natural alcohols and derivatives with calcium carbide

Vinyl ethers are essential synthetic building blocks for organic synthesis, especially for polymer synthesis and highly vinylated polyol substrates. Herein, a transition metal-free, mild, and safe protocol has been developed for direct vinylation of natural alcohols with calcium carbide. Various sugar alcohols, phenol and its derivatives were tested and proved successful using this green methodology. Selectivity of full vinylated products of the reaction decreases with increasing hydroxyl groups because of side reactions occurring under the basic medium. Electron-donating substituted phenols work more efficiently than electron-withdrawing substituted phenols in general. This methodology may provide new insights on selective vinylation of electron-rich biomass-derived materials.

Bis(aryl)acetal compounds

A bis(aryl)acetal has the formula wherein Y1 and Y2 are each independently chloro, bromo, iodo, mesylate, tosylate, triflate, or Bx, provided that Y1 and Y2 are not both selected from chloro, bromo, a

New pyrrolidine derivatives, pharmaceutical compositions and uses thereof

Pyrrolidine derivatives of the formula and their use as medicaments for the treatment of obesity and type 2 diabetes.

NEW PYRROLIDINE DERIVATIVES AND THEIR USE AS ACETYL-COA CARBOXYLASE INHIBITORS

The invention relates to new pyrrolidine derivatives of the formula (I) to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them.

Design and controlled synthesis by dual polymerization of new organic-inorganic hybrid material for photonic devices

Organic-inorganic hybrid material was synthesized by double polymerization processes i.e. a sol-gel process and organic polymerization respectively. For this study, hybrid monomer, 4-vinyl ether-phenyltriethoxysilane (VEPTES) was used as starting building block. First, the silica matrix with tunable ratio of siloxane and silanol units was synthesized by a sol-gel process under acidic conditions and the organic network was formed by cationic photopolymerization of vinyl ether groups. Mineral and organic polymerization kinetics were respectively monitored by liquid 29Si-NMR and IR spectroscopy. The effect of the silicate backbone on the organic photopolymerization process was studied and elucidated. The optical performance of this new hybrid material has been studied using the near-infrared spectroscopy.

PIPERIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF

The invention relates to new piperidine derivatives of the formula (I) to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them.

New piperidine derivatives, pharmaceutical compositions and uses thereof

The invention relates to new piperidine derivatives of the formula I to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them.

NEW AZIRIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE AS ACETYL-COA CARBOXYLASE INHIBITORS

The invention relates to new azetidine derivatives of the formula (I) wherein Ar1, Ar2, X, R, T and L are as defined in the description, to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them.