1-Cyclohexyl-3-(4-hydroxyphenyl)urea

Base Information

Chemical Name:1-Cyclohexyl-3-(4-hydroxyphenyl)urea
CAS No.:38652-23-2
Molecular Formula:C13H18N2O2
Molecular Weight:234.298
Hs Code.:2924299090
DSSTox Substance ID:DTXSID70398784
Nikkaji Number:J2.090.826B
Wikidata:Q82200951
ChEMBL ID:CHEMBL11522
Mol file:38652-23-2.mol

Synonyms:1-cyclohexyl-3-(4-hydroxyphenyl)urea;38652-23-2;CHEMBL11522;N-Cyclohexyl-N'-(4-hydroxyphenyl)urea;SCHEMBL12196184;DTXSID70398784;BDBM50124657;AKOS009144421;1-Cyclohexyl-3-(4-hydroxy-phenyl)-urea;FT-0665357;US8815951, 128

Suppliers and Price of 1-Cyclohexyl-3-(4-hydroxyphenyl)urea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Cyclohexyl-3-(4-hydroxyphenyl)urea
5g
$ 1815.00

Biosynth Carbosynth
1-Cyclohexyl-3-(4-hydroxyphenyl)urea
5 g
$ 2870.00

Biosynth Carbosynth
1-Cyclohexyl-3-(4-hydroxyphenyl)urea
2 g
$ 1360.00

American Custom Chemicals Corporation
1-CYCLOHEXYL-3-(4-HYDROXYPHENYL)UREA 95.00%
5MG
$ 499.74

Total 4 raw suppliers

Chemical Property of 1-Cyclohexyl-3-(4-hydroxyphenyl)urea

Chemical Property:

Melting Point:>200°C (dec.)
PSA：64.85000
LogP:3.12380
Storage Temp.:Refrigerator
Solubility.:DMSO, Methanol
XLogP3:2.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:234.136827821
Heavy Atom Count:17
Complexity:244

Purity/Quality:

99% ^*data from raw suppliers

1-Cyclohexyl-3-(4-hydroxyphenyl)urea ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(CC1)NC(=O)NC2=CC=C(C=C2)O

Technology Process of 1-Cyclohexyl-3-(4-hydroxyphenyl)urea

There total 4 articles about 1-Cyclohexyl-3-(4-hydroxyphenyl)urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 123-30-8
4-amino-phenol

: 3173-53-3
Cyclohexyl isocyanate

: 38652-23-2
1-cyclohexyl-3-(4-hydroxyphenyl)urea

Guidance literature:: With pyridine; for 6h;
DOI:10.1021/ol040042i

Reference yield:

: 2-(4-isocyanatophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 108-91-8,157973-60-9
cyclohexylamine

: 38652-23-2
1-cyclohexyl-3-(4-hydroxyphenyl)urea

Guidance literature:: 2-(4-isocyanatophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; cyclohexylamine; With triethylamine; In dichloromethane; at 48 ℃; for 2h; Cooling with ice;

With dihydrogen peroxide; In methanol; at 20 ℃; for 2h;
DOI:10.1002/jhet.4287

Reference yield:

: 214360-73-3
4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)aniline

: 38652-23-2
1-cyclohexyl-3-(4-hydroxyphenyl)urea

Guidance literature:: Multi-step reaction with 2 steps

1.1: dichloromethane / 1.17 h

2.1: triethylamine / dichloromethane / 2 h / 48 °C / Cooling with ice

2.2: 2 h / 20 °C

With triethylamine; In dichloromethane;
DOI:10.1002/jhet.4287