Dehydrobaimuxinol

Base Information

• Chemical Name: Dehydrobaimuxinol
• CAS No.: 105013-74-9
• Molecular Formula: C15H24O2
• Molecular Weight: 236.34986
• Mol file: 105013-74-9.mol

Synonyms:Dehydrobaimuxinol

Chemical Property of Dehydrobaimuxinol

Chemical Property:

• Vapor Pressure: 6.03E-06mmHg at 25°C
• Boiling Point: 339.7°Cat760mmHg
• Flash Point: 138.3°C
• PSA: 29.46000
• Density: 1.08g/cm³
• LogP: 3.05290

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Dehydrobaimuxinol

There total 4 articles about Dehydrobaimuxinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

(+)-12-Oxo-α-agarofuran (141422-50-6) → dehydrobaimuxinol (105013-74-9)

Guidance literature:

With sodium tetrahydroborate; In methanol; for 3.5h; Ambient temperature;

DOI:10.1080/00397919208021104 DOI:10.1055/s-1992-26299

Reference yield: 50.0%

5,11-oxy-5β,10α-eudesm-3-ene (5956-12-7) → dehydrobaimuxinol (105013-74-9) + (+)-12-Oxo-α-agarofuran (141422-50-6)

Guidance literature:

With selenium(IV) oxide; silica gel; In 1,4-dioxane; for 12h; Heating;

DOI:10.1039/a704440b

Reference yield:

10-epieudesm-4-ene-3,11-diols (849949-32-2) → dehydrobaimuxinol (105013-74-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 73 percent / conc. H₂SO₄ / benzene / 0.17 h / Ambient temperature

2: 35 percent / 5percent SeO₂/silica gel / dioxane / 1 h / Ambient temperature

With selenium(IV) oxide; sulfuric acid; silica gel; In 1,4-dioxane; benzene;

DOI:10.1055/s-1992-26299

upstream raw materials:

5,11-oxy-5β,10α-eudesm-3-ene

(+)-12-Oxo-α-agarofuran

10-epieudesm-4-ene-3,11-diols

Downstream raw materials:

(-)-Baimuxinol

(-)-Isobaimuxinol

Refernces

• 1、 Chen, Yonggang,Xiong, Zhaoming,Yang, Jiong,Li, Yulin. "Total Synthesis of ( - )-Baimuxifuranic Acid". . p. 472 - 473. Retrieved 2007/10/03.