1-(3,4,5-TRIMETHOXYPHENYL)-PIPERAZINE HYDROCHLORIDE

Base Information

• Chemical Name: 1-(3,4,5-TRIMETHOXYPHENYL)-PIPERAZINE HYDROCHLORIDE
• CAS No.: 38869-07-7
• Molecular Formula: C13H20N2O3
• Molecular Weight: 252.313
• Hs Code.: 2933599090
• Mol file: 38869-07-7.mol

Synonyms:1-(3,4,5-TRIMETHOXYPHENYL)-PIPERAZINE HYDROCHLORIDE;4-(3,4,5-trimethoxyphenyl)piperazine;1-(3',4',5'-Trimethoxyphenyl)-piperazin;1-(3,4,5-trimethoxyphenyl)piperazine;N-(3,4,5-trimethoxyphenyl)-piperazine;

Chemical Property of 1-(3,4,5-TRIMETHOXYPHENYL)-PIPERAZINE HYDROCHLORIDE

Chemical Property:

• Melting Point: 210oC (dec.)
• PSA: 42.96000
• LogP: 2.31780

Purity/Quality:

99% ^*data from raw suppliers

1-(3,4,5-TRIMETHOXYPHENYL)PIPERAZINE HYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(3,4,5-TRIMETHOXYPHENYL)-PIPERAZINE HYDROCHLORIDE

There total 4 articles about 1-(3,4,5-TRIMETHOXYPHENYL)-PIPERAZINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bis-(2-chloroethyl)amine hydrochloride (821-48-7) + 3,4,5-Trimethoxyaniline (24313-88-0) → N-(3,4,5-trimethoxyphenyl)-piperazine (38869-07-7)

Guidance literature:

With potassium carbonate; In sodium hydroxide; ethanol;

Reference yield:

concentrated aqueous potassium hydroxide + bis-(2-chloroethyl)amine hydrochloride (821-48-7) + 3,4,5-Trimethoxyaniline (24313-88-0) → N-(3,4,5-trimethoxyphenyl)-piperazine (38869-07-7)

Guidance literature:

With potassium carbonate; In diethylene glycol dimethyl ether; water;

Reference yield:

bis(2-bromoethyl)amine hydrobromide (43204-63-3) + 3,4,5-Trimethoxyaniline (24313-88-0) → 4-(3,4,5-trimethoxyphenyl)piperazine monohydrobromide + N-(3,4,5-trimethoxyphenyl)-piperazine (38869-07-7)

Guidance literature:

With sodium carbonate; In methanol;

upstream raw materials:

bis-(2-chloroethyl)amine hydrochloride

3,4,5-Trimethoxyaniline

bis(2-bromoethyl)amine hydrobromide

Downstream raw materials:

N-(3,4,5-trimethoxy-benzyl)-N'-(3,4,5-trimethoxyphenyl)-piperazine hydrochloride

5-[4-(3,4,5-trimethoxyphenyl)piperazin-1-yl]pyrrolidin-2-one

N-[2-(dimethylamino)ethyl]-4-(3,4,5-trimethoxyphenyl)-1-piperazinecarboxamide

5,8-Dimethoxy-2,3-bis-{4-[4-(3,4,5-trimethoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-quinoxaline

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