5-[(2-Chlorophenyl)methyl]-1,3,4-thiadiazol-2-amine

Base Information

Chemical Name:5-[(2-Chlorophenyl)methyl]-1,3,4-thiadiazol-2-amine
CAS No.:39181-47-0
Molecular Formula:C9H8ClN3S
Molecular Weight:225.702
Hs Code.:
DSSTox Substance ID:DTXSID101224602
Mol file:39181-47-0.mol

Synonyms:39181-47-0;5-(2-Chlorobenzyl)-1,3,4-thiadiazol-2-amine;5-[(2-chlorophenyl)methyl]-1,3,4-thiadiazol-2-amine;SCHEMBL2197478;XUNCENJKWCLCAM-UHFFFAOYSA-N;DTXSID101224602;MFCD02664103;SY318047;5-(2-Chloro-benzyl)-[1,3,4]thiadiazol-2-ylamine

Suppliers and Price of 5-[(2-Chlorophenyl)methyl]-1,3,4-thiadiazol-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 5-[(2-Chlorophenyl)methyl]-1,3,4-thiadiazol-2-amine

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:225.0127461
Heavy Atom Count:14
Complexity:193

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)CC2=NN=C(S2)N)Cl

Technology Process of 5-[(2-Chlorophenyl)methyl]-1,3,4-thiadiazol-2-amine

There total 4 articles about 5-[(2-Chlorophenyl)methyl]-1,3,4-thiadiazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 2444-36-2
2'-chloro-benzeneacetic acid

: 79-19-6
thiosemicarbazide

: 39181-47-0
2-amino-5-o-chlorophenylmethyl-1,3,4-thiadiazole

Guidance literature:: With trichlorophosphate; at 75 ℃; for 6h; Cooling with ice;
DOI:10.3184/174751916X14494964318204

Reference yield:

: 2444-36-2
2'-chloro-benzeneacetic acid

: 79-19-6
thiosemicarbazide

: 862574-67-2
N-[5-(2-chloro-benzyl)-[1,3,4]thiadiazol-2-yl]-2-(2-chloro-phenyl)-acetamide

: 39181-47-0
2-amino-5-o-chlorophenylmethyl-1,3,4-thiadiazole

Guidance literature:: 2'-chloro-benzeneacetic acid; thiosemicarbazide; With trichlorophosphate; In 1,4-dioxane; at 90 ℃; for 2h;

With sodium hydroxide; In water;

Reference yield:

: 862574-67-2
N-[5-(2-chloro-benzyl)-[1,3,4]thiadiazol-2-yl]-2-(2-chloro-phenyl)-acetamide

: 39181-47-0
2-amino-5-o-chlorophenylmethyl-1,3,4-thiadiazole

Guidance literature:: N-[5-(2-chloro-benzyl)-[1,3,4]thiadiazol-2-yl]-2-(2-chloro-phenyl)-acetamide; With hydrogenchloride; ethanol; water; for 15h; Heating / reflux;

With sodium carbonate; In water;