(E)-1-Methoxy-3-(prop-1-en-1-yl)benzene

Base Information

• Chemical Name: (E)-1-Methoxy-3-(prop-1-en-1-yl)benzene
• CAS No.: 52956-26-0
• Molecular Formula: C10H12O
• Molecular Weight: 148.205
• Nikkaji Number: J141.460G,J510.872A
• Mol file: 52956-26-0.mol

Synonyms:(E)-1-Methoxy-3-(prop-1-en-1-yl)benzene;52956-26-0;Benzene, 1-methoxy-3-(1-propenyl)-, (E)-;ghl.PD_Mitscher_leg0.30;SCHEMBL257114;3-[(E)-1-Propenyl]anisole;1-Methoxy-3-(1-propenyl)benzene

Chemical Property of (E)-1-Methoxy-3-(prop-1-en-1-yl)benzene

Chemical Property:

• Vapor Pressure: 0.12mmHg at 25°C
• Boiling Point: 226.8°C at 760 mmHg
• Flash Point: 83.5°C
• Density: 0.959g/cm³
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 148.088815002
• Heavy Atom Count: 11
• Complexity: 129

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC=CC1=CC(=CC=C1)OC
• Isomeric SMILES: C/C=C/C1=CC(=CC=C1)OC

Technology Process of (E)-1-Methoxy-3-(prop-1-en-1-yl)benzene

There total 28 articles about (E)-1-Methoxy-3-(prop-1-en-1-yl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1-methoxy-3-(prop-1-en-1-yl)benzene (20112-91-8) → (E)-1-methoxy-3-(prop-1-en-1-yl)benzene (52956-26-0)

Guidance literature:

With dichloro bis(acetonitrile) palladium(II); In dichloromethane; at 20 ℃; for 14h;

DOI:10.1021/jo015880u

Reference yield: 96.0%

(Z)-1-methoxy-3-(prop-1-en-1-yl)benzene (74254-18-5) → (E)-1-methoxy-3-(prop-1-en-1-yl)benzene (52956-26-0)

Guidance literature:

With sodium triethylborohydride; cobalt(II) chloride; In toluene; at 25 ℃; for 0.166667h; stereoselective reaction;

Reference yield: 95.0%

ethyltriphenylphosphonium bromide (1530-32-1) + 3-methoxy-benzaldehyde (591-31-1) → (E)-1-methoxy-3-(prop-1-en-1-yl)benzene (52956-26-0)

Guidance literature:

ethyltriphenylphosphonium bromide; With n-butyllithium; In tetrahydrofuran; at -78 - 0 ℃; Inert atmosphere;

3-methoxy-benzaldehyde; In tetrahydrofuran; at -78 - 25 ℃; for 3.83333h; Inert atmosphere;

With dichloro bis(acetonitrile) palladium(II); In chloroform; at 25 ℃; for 72h;

DOI:10.3998/ark.5550190.0011.206

upstream raw materials:

diazomethane

(E)-3-(prop-1-en-1-yl)phenol

1-allyl-3-methoxybenzene

(1RS,2RS)-2-diphenylphosphinoyl-1-(3-methoxyphenyl)propan-1-ol

Downstream raw materials:

(E)-m-methoxycinnamaldehyde

3-methoxy-benzaldehyde

(Z)-1-methoxy-3-(prop-1-en-1-yl)benzene

1-(3-methoxyphenyl)propan-2-yl acetate