Technology Process of (1R,4S)-2-Cyclohexene-1,4-dicarboxylic acid
There total 21 articles about (1R,4S)-2-Cyclohexene-1,4-dicarboxylic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
carbon dioxide; cyclohexa-1,3-diene;
With
bis(1,5-cyclooctadiene)nickel (0); 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
tetrahydrofuran;
at 0 ℃;
for 7h;
under 760.051 Torr;
carbon dioxide;
With
dimethyl zinc(II);
In
tetrahydrofuran;
at 0 ℃;
for 2h;
Further stages.;
DOI:10.1021/ja004004f
- Guidance literature:
-
Multi-step reaction with 2 steps
1: Cu2Cl2, nPrCO2Na, PdCl2, HC(OMe)3 / 2280 Torr
2: (hydrolysis)
With
copper(I) chloride; sodium butyrate; palladium dichloride; trimethyl orthoformate;
DOI:10.1021/jo01334a006
- Guidance literature:
-
Multi-step reaction with 2 steps
1: Cu2Cl2, nPrCO2Na, PdCl2, HC(OMe)3 / 2280 Torr
2: (hydrolysis)
With
copper(I) chloride; sodium butyrate; palladium dichloride; trimethyl orthoformate;
DOI:10.1021/jo01334a006