cis-1,4-Cyclohexanedicarboxybic acid

Base Information

• Chemical Name: cis-1,4-Cyclohexanedicarboxybic acid
• CAS No.: 619-81-8
• Molecular Formula: C8H12O4
• Molecular Weight: 172.181
• Hs Code.: 29172090
• Mol file: 619-81-8.mol

Synonyms:1,4-cis-Cyclohexanedicarboxylicacid;cis-1,4-Cyclohexanedicarboxylic acid;cis-Hexahydroterephthalic acid;

Chemical Property of cis-1,4-Cyclohexanedicarboxybic acid

Chemical Property:

• Melting Point: 168 °C
• Boiling Point: 384.1 °C at 760 mmHg
• PKA: 4.51±0.25(Predicted)
• Flash Point: 200.3 °C
• PSA: 74.60000
• Density: 1.314 g/cm³
• LogP: 0.96200
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: soluble in Ethanol,Ether,Chloroform,Methanol

Purity/Quality:

98%,99%, ^*data from raw suppliers

cis-1,2-Cyclohexanedicarboxylic Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of cis-1,4-Cyclohexanedicarboxybic acid

There total 45 articles about cis-1,4-Cyclohexanedicarboxybic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

dimethyl 1,4-cyclohexane dicarboxylate (94-60-0) → cyclohexane-1,4-dicarboxylic acid (619-81-8,619-82-9,1076-97-7)

Guidance literature:

With sulfuric acid; In water; at 100 ℃; for 3h; Reagent/catalyst; Temperature;

Reference yield: 68.0%

disodium 1,4-cyclohexanedicarboxylate → cyclohexane-1,4-dicarboxylic acid (619-81-8,619-82-9,1076-97-7)

Guidance literature:

With hydrogenchloride; at 10 ℃;

Reference yield:

bis-1,4-(hydroxymethyl)cyclohexane (105-08-8) → cyclohexane-1,4-dicarboxylic acid (619-81-8,619-82-9,1076-97-7)

Guidance literature:

With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; potassium chloride; oxygen; ferric nitrate; In 1,2-dichloro-ethane; at 20 ℃; for 24h;

upstream raw materials:

iodomethane-d3

bis-1,4-(hydroxymethyl)cyclohexane

ethyl iodide

dimethyl 1,4-cyclohexane dicarboxylate

Downstream raw materials:

(1S,4S)-4-(methoxycarbonyl)cyclohexane-1-carboxylic acid

trans-hexahydroterephthalic acid

cis-dimethyl 1,4-cyclohexanedicarboxylate

cyclohexane-1,4-dicarbonitrile

Refernces

• 1、 -. "PRODUCTION METHOD FOR 1,4-CYCLOHEXANEDICARBOXYLIC ACID DERIVATIVE, 1,4-DICYANOCYCLOHEXANE AND 1,4-BIS(AMINOMETHYL)CYCLOHEXANE". Paragraph 0066; 0067; 0089. . Retrieved 2021/02/05.
• 2、 -. "Catalyst for aqueous phase catalytic hydrogenation of phthalic acids and ester derivatives thereof and preparation method and application thereof". Paragraph 0046-0051; 0055-0056. . Retrieved 2020/07/13.