Benzene, [[[(1R,2S,3R)-2-(iodomethyl)-3-(2-phenylethyl)cyclopropyl]methyl]thio]-

Base Information

Chemical Name:Benzene, [[[(1R,2S,3R)-2-(iodomethyl)-3-(2-phenylethyl)cyclopropyl]methyl]thio]-
CAS No.:392655-69-5
Molecular Formula:C19H21IS
Molecular Weight:408.346
Hs Code.:
Mol file:392655-69-5.mol

Synonyms:

Suppliers and Price of Benzene, [[[(1R,2S,3R)-2-(iodomethyl)-3-(2-phenylethyl)cyclopropyl]methyl]thio]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Benzene, [[[(1R,2S,3R)-2-(iodomethyl)-3-(2-phenylethyl)cyclopropyl]methyl]thio]-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Benzene, [[[(1R,2S,3R)-2-(iodomethyl)-3-(2-phenylethyl)cyclopropyl]methyl]thio]-

There total 9 articles about Benzene, [[[(1R,2S,3R)-2-(iodomethyl)-3-(2-phenylethyl)cyclopropyl]methyl]thio]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 392656-14-3
((1S,2S,3R)-2-Phenethyl-3-phenylsulfanylmethyl-cyclopropyl)-methanol

: 392655-69-5
(1S,2R,3R)-1-iodomethyl-2-phenethyl-3-(phenylthiomethyl)cyclopropane

Guidance literature:: With 1H-imidazole; iodine; triphenylphosphine; In benzene; at 20 ℃; for 0.25h;
DOI:10.1021/jo010728d

Reference yield:

: 58506-33-5
5-phenyl-trans,trans-2,4-pentadien-1-ol

: 392655-69-5
(1S,2R,3R)-1-iodomethyl-2-phenethyl-3-(phenylthiomethyl)cyclopropane

Guidance literature:: Multi-step reaction with 9 steps

1: 87 percent / 120 °C / 70 Torr

2: 66 percent / tosyl azide; tetrabutylammonium bromide; aq. NaOH / CH₂Cl₂ / 20 °C

3: 51 percent / CuSO₄; Cu(aca)2 / benzene / Heating

4: 87 percent / LiAlH₄ / tetrahydrofuran / 20 °C

5: 93 percent / Pseudomonas fluorescens lipase AK / benzene / 3 h / 20 °C

6: 95 percent / H₂ / Pd/C / ethanol / 3 h / 20 °C / 2660.18 Torr

7: 99 percent / tri-n-butylphosphine / pyridine / 1 h / 20 °C

8: 100 percent / aq. KOH / ethanol / 0.5 h / 20 °C

9: 81 percent / imidazole; Ph₃P; I₂ / benzene / 0.25 h / 20 °C

With 1H-imidazole; potassium hydroxide; sodium hydroxide; lithium aluminium tetrahydride; 4-toluenesulfonyl azide; tributylphosphine; Cu(aca)2; Pseudomonas fluorescens lipase AK; tetrabutylammomium bromide; hydrogen; iodine; copper(II) sulfate; triphenylphosphine; palladium on activated charcoal; In tetrahydrofuran; pyridine; ethanol; dichloromethane; benzene;
DOI:10.1021/jo010728d

Reference yield:

: 1-oxo-4-styryl-1,3,3a,4a-tetrahydrocyclopropa[c]furan

: 392655-69-5
(1S,2R,3R)-1-iodomethyl-2-phenethyl-3-(phenylthiomethyl)cyclopropane

Guidance literature:: Multi-step reaction with 6 steps

1: 87 percent / LiAlH₄ / tetrahydrofuran / 20 °C

2: 93 percent / Pseudomonas fluorescens lipase AK / benzene / 3 h / 20 °C

3: 95 percent / H₂ / Pd/C / ethanol / 3 h / 20 °C / 2660.18 Torr

4: 99 percent / tri-n-butylphosphine / pyridine / 1 h / 20 °C

5: 100 percent / aq. KOH / ethanol / 0.5 h / 20 °C

6: 81 percent / imidazole; Ph₃P; I₂ / benzene / 0.25 h / 20 °C

With 1H-imidazole; potassium hydroxide; lithium aluminium tetrahydride; tributylphosphine; Pseudomonas fluorescens lipase AK; hydrogen; iodine; triphenylphosphine; palladium on activated charcoal; In tetrahydrofuran; pyridine; ethanol; benzene;
DOI:10.1021/jo010728d