[5-(4-Fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](morpholin-4-yl)methanone

Base Information

Chemical Name:[5-(4-Fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](morpholin-4-yl)methanone
CAS No.:5843-01-6
Molecular Formula:C18H14F4N4O2
Molecular Weight:394.323
Hs Code.:
DSSTox Substance ID:DTXSID30360422
Wikidata:Q82142156
ChEMBL ID:CHEMBL1459678

Synonyms:MLS000109354;SMR000105297;[5-(4-fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](morpholin-4-yl)methanone;5843-01-6;CBMicro_035058;SCHEMBL4211288;CHEMBL1459678;BDBM89775;cid_1110941;DTXSID30360422;OGFLEYWTLFIGRT-UHFFFAOYSA-N;HMS2291A16;STK342947;AKOS000560843;CCG-198381;[5-(4-fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-morpholin-4-ylmethanone;BIM-0034990.P001;EU-0060363;SR-01000550801;SR-01000550801-1;[5-(4-fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-morpholino-methanone;[5-(4-fluorophenyl)-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinyl]-(4-morpholinyl)methanone;[5-(4-fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-morpholin-4-yl-methanone

Suppliers and Price of [5-(4-Fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](morpholin-4-yl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of [5-(4-Fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](morpholin-4-yl)methanone

Chemical Property:

Density:1.51g/cm³
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:2
Exact Mass:394.10528835
Heavy Atom Count:28
Complexity:564

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1C(=O)C2=NN3C(=CC(=NC3=C2)C4=CC=C(C=C4)F)C(F)(F)F

Technology Process of [5-(4-Fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](morpholin-4-yl)methanone

There total 2 articles about [5-(4-Fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](morpholin-4-yl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1906-47-4
benzoic acid-[N'-(2-cyano-ethyl)-hydrazide]

: 5843-01-6
benzoic acid-[N'-(3-amino-propyl)-hydrazide]

Guidance literature:: With ammonia; nickel; at 80 ℃; under 73550.8 Torr; Hydrogenation;
DOI:10.1002/hlca.19590420224

Reference yield:

: 613-94-5
benzoic acid hydrazide

: 5843-01-6
benzoic acid-[N'-(3-amino-propyl)-hydrazide]

Guidance literature:: Multi-step reaction with 2 steps

2: LiAlH₄; THF

With tetrahydrofuran; lithium aluminium tetrahydride;
DOI:10.1002/hlca.19590420224