N-[4-[3-[4-(Dimethylamino)phenyl]-2-propenoyl]phenyl]acetamide

Base Information

Chemical Name:N-[4-[3-[4-(Dimethylamino)phenyl]-2-propenoyl]phenyl]acetamide
CAS No.:5336-80-1
Molecular Formula:C19H20N2O2
Molecular Weight:308.38
Hs Code.:
NSC Number:373
Mol file:5336-80-1.mol

Synonyms:NSC373;N-[4-[3-[4-(DIMETHYLAMINO)PHENYL]-2-PROPENOYL]PHENYL]ACETAMIDE;5336-80-1;NSC-373;PNSVICPSMTUZNX-AWNIVKPZSA-N;4'-Acetamido-4-dimethylaminochalcone;STK156222;AKOS001711651;Acetanilide, 4'-[p-(dimethylamino)-cinnamoyl]-;Acetamide, N-[4-[3-(4-dimethylaminophenyl)-1-oxopropenyl]phenyl]-;N-(4-(3-[4-(Dimethylamino)phenyl]-2-propenoyl)phenyl)acetamide #;Acetamide, N-[4-[3-[4-(dimethylamino)phenyl]-1-oxo-2-propenyl]phenyl]-;N-(4-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-enoyl}phenyl)acetamide;N~1~-(4-{(E)-3-[4-(dimethylamino)phenyl]-2-propenoyl}phenyl)acetamide

Suppliers and Price of N-[4-[3-[4-(Dimethylamino)phenyl]-2-propenoyl]phenyl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of N-[4-[3-[4-(Dimethylamino)phenyl]-2-propenoyl]phenyl]acetamide

Chemical Property:

Vapor Pressure:1.44E-12mmHg at 25°C
Boiling Point:559.9°C at 760 mmHg
Flash Point:292.4°C
Density:1.181g/cm³
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:308.152477885
Heavy Atom Count:23
Complexity:429

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=CC=C(C=C1)C(=O)C=CC2=CC=C(C=C2)N(C)C
Isomeric SMILES:CC(=O)NC1=CC=C(C=C1)C(=O)/C=C/C2=CC=C(C=C2)N(C)C

Technology Process of N-[4-[3-[4-(Dimethylamino)phenyl]-2-propenoyl]phenyl]acetamide

There total 4 articles about N-[4-[3-[4-(Dimethylamino)phenyl]-2-propenoyl]phenyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 100-10-7
4-dimethylamino-benzaldehyde

: 2719-21-3,150667-24-6
4-(N-acetylamino)acetophenone

: 5336-80-1
N-(4′-[(2E)-3-(4-dimethylaminophenyl)-1-(phenyl)prop-2-en-1-one])acetamide

Guidance literature:: With sodium hydroxide; In methanol; water; at 20 ℃;
DOI:10.3390/12040896

Reference yield: 60.4%

: 108-24-7
acetic anhydride

: 126443-09-2
1-(4-aminophenyl)-3-<4-(dimethylamino)phenyl>prop-2-en-1-one

: 5336-80-1
N-(4′-[(2E)-3-(4-dimethylaminophenyl)-1-(phenyl)prop-2-en-1-one])acetamide

Guidance literature:: With sodium acetate; acetic acid; In aq. buffer; for 1h; pH=5;
DOI:10.1007/s00044-019-02434-1

Reference yield:

: 99-92-3
p-aminobenzophenone

: 5336-80-1
N-(4′-[(2E)-3-(4-dimethylaminophenyl)-1-(phenyl)prop-2-en-1-one])acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / H₂O / 2 h / Heating

2: 72 percent / NaOH / H₂O; methanol / 20 °C

With sodium hydroxide; In methanol; water;
DOI:10.3390/12040896