1-Piperazinecarboxylic acid, 4-(4-amino-2-methoxyphenyl)-, 1,1-dimethylethyl ester

Base Information

Chemical Name:1-Piperazinecarboxylic acid, 4-(4-amino-2-methoxyphenyl)-, 1,1-dimethylethyl ester
CAS No.:394249-00-4
Molecular Formula:C16H25N3O3
Molecular Weight:307.393
Hs Code.:

Synonyms:4-(4-Amino-2-methoxy-phenyl)-piperazine-1-carboxylic acid tert-butyl ester;1-(4-amino-2-methoxyphenyl)-4-tert-butoxycarbonylpiperazine;

Suppliers and Price of 1-Piperazinecarboxylic acid, 4-(4-amino-2-methoxyphenyl)-, 1,1-dimethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynChem
4-(4-Amino-2-methoxy-phenyl)-piperazine-1-carboxylic acid tert-butyl ester 95+%
5 g
$ 685.00

SynChem
4-(4-Amino-2-methoxy-phenyl)-piperazine-1-carboxylic acid tert-butyl ester 95+%
1 g
$ 215.00

Abosyn
tert-butyl4-(4-amino-2-methoxyphenyl)piperazine-1-carboxylate 95%-98%
1g
$ 810.00

Total 6 raw suppliers

Chemical Property of 1-Piperazinecarboxylic acid, 4-(4-amino-2-methoxyphenyl)-, 1,1-dimethylethyl ester

Chemical Property:

PSA：68.03000
LogP:2.91860

Purity/Quality:

99% ^*data from raw suppliers

4-(4-Amino-2-methoxy-phenyl)-piperazine-1-carboxylic acid tert-butyl ester 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-Piperazinecarboxylic acid, 4-(4-amino-2-methoxyphenyl)-, 1,1-dimethylethyl ester

There total 8 articles about 1-Piperazinecarboxylic acid, 4-(4-amino-2-methoxyphenyl)-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.3%

: 394248-99-8
4-(2-methoxy-4-nitrophenyl)piperazine-1-carboxylic acid tert-butyl ester

: 394249-00-4
4-(4-amino-2-methoxyphenyl)piperazine-1-carboxylic acid tert-butyl ester

Guidance literature:: With palladium on activated charcoal; hydrogen; In methanol; at 20 ℃; for 2h;

Reference yield:

: 433214-09-6
1-(4-amino-2-methoxyphenyl)piperazine

: 24424-99-5
di-tert-butyl dicarbonate

: 394249-00-4
4-(4-amino-2-methoxyphenyl)piperazine-1-carboxylic acid tert-butyl ester

Guidance literature:: With sodium hydroxide; In tetrahydrofuran;

Reference yield:

: 170912-81-9
1-(2-methoxy-4-nitro-phenyl)-piperazine

: 394249-00-4
4-(4-amino-2-methoxyphenyl)piperazine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / CH₂Cl₂

2: H₂ / Pd/C / ethanol

With hydrogen; palladium on activated charcoal; In ethanol; dichloromethane;
DOI:10.1016/j.bmcl.2006.06.061