1-(2-Hydroxy-4,6-dimethoxyphenyl)-2-(4-methoxyphenyl)ethanone

Base Information

Chemical Name:1-(2-Hydroxy-4,6-dimethoxyphenyl)-2-(4-methoxyphenyl)ethanone
CAS No.:39604-68-7
Molecular Formula:C17H18O5
Molecular Weight:302.327
Hs Code.:2914509090
European Community (EC) Number:650-979-9
DSSTox Substance ID:DTXSID30351017
Nikkaji Number:J1.191.741K
Wikidata:Q82127110
ChEMBL ID:CHEMBL1784921
Mol file:39604-68-7.mol

Synonyms:1-(2-hydroxy-4,6-dimethoxyphenyl)-2-(4-methoxyphenyl)ethanone;39604-68-7;1-(2-hydroxy-4,6-dimethoxyphenyl)-2-(4-methoxyphenyl)ethan-1-one;Ethanone, 1-(2-hydroxy-4,6-dimethoxyphenyl)-2-(4-methoxyphenyl)-;2'-Hydroxy-4',6'-dimethoxy-2-(4-methoxyphenyl)acetophenone;CHEMBL1784921;DTXSID30351017;MFCD03934798;AKOS024282690;BS-44134;CS-0332447;H1578;T72424;2-Hydroxy-4,6-dimethoxyphenyl 4-Methoxybenzyl Ketone

Suppliers and Price of 1-(2-Hydroxy-4,6-dimethoxyphenyl)-2-(4-methoxyphenyl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TCI Chemical
2'-Hydroxy-4',6'-dimethoxy-2-(4-methoxyphenyl)acetophenone >98.0%(GC)
5g
$ 273.00

TCI Chemical
2'-Hydroxy-4',6'-dimethoxy-2-(4-methoxyphenyl)acetophenone >98.0%(GC)
1g
$ 83.00

American Custom Chemicals Corporation
1-(2-HYDROXY-4,6-DIMETHOXYPHENYL)-2-(4-METHOXYPHENYL)ETHANONE 95.00%
1G
$ 708.25

American Custom Chemicals Corporation
1-(2-HYDROXY-4,6-DIMETHOXYPHENYL)-2-(4-METHOXYPHENYL)ETHANONE 95.00%
250MG
$ 579.69

AK Scientific
1-(2-Hydroxy-4,6-dimethoxyphenyl)-2-(4-methoxyphenyl)ethanone
5g
$ 433.00

Total 6 raw suppliers

Chemical Property of 1-(2-Hydroxy-4,6-dimethoxyphenyl)-2-(4-methoxyphenyl)ethanone

Chemical Property:

Melting Point:85.0 to 89.0 °C
Boiling Point:494.8±40.0 °C(Predicted)
PKA:7.07±0.40(Predicted)
PSA：64.99000
Density:1.199±0.06 g/cm3(Predicted)
LogP:2.84340
Solubility.:soluble in Toluene
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:302.11542367
Heavy Atom Count:22
Complexity:351

Purity/Quality:

97% ^*data from raw suppliers

2'-Hydroxy-4',6'-dimethoxy-2-(4-methoxyphenyl)acetophenone >98.0%(GC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)CC(=O)C2=C(C=C(C=C2OC)OC)O

Technology Process of 1-(2-Hydroxy-4,6-dimethoxyphenyl)-2-(4-methoxyphenyl)ethanone

There total 14 articles about 1-(2-Hydroxy-4,6-dimethoxyphenyl)-2-(4-methoxyphenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 15485-66-2
2,4,6-trihydroxy-4'-methoxydeoxybenzoin

: 39604-68-7
2'-hydroxy-4',6-dimethoxy-2-(p-methoxyphenyl)acetophenone

Guidance literature:: In methanol; diethyl ether; at 0 ℃;
DOI:10.1055/s-1998-2221

Reference yield: 33.0%

: 104-01-8
4-Methoxyphenylacetic acid

: 621-23-8
1,2,3-trimethoxybenzene

: 39604-68-7
2'-hydroxy-4',6-dimethoxy-2-(p-methoxyphenyl)acetophenone

Guidance literature:: With boron trifluoride diethyl etherate; at 70 ℃; for 12h;
DOI:10.1016/S0040-4020(99)00993-X

Reference yield:

: 117828-32-7
4,6-dihydroxy-2-(4-methoxyphenyl)benzofuran-3(2H)-one

: 39604-68-7
2'-hydroxy-4',6-dimethoxy-2-(p-methoxyphenyl)acetophenone

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Pd-C / ethanol

2: K₂CO₃ / acetone / Heating

With hydrogen; potassium carbonate; palladium on activated charcoal; In ethanol; acetone;