2-NITROSTYRENE OXIDE)

Base Information

• Chemical Name: 2-NITROSTYRENE OXIDE)
• CAS No.: 39830-70-1
• Molecular Formula: C8H7NO3
• Molecular Weight: 165.148
• Mol file: 39830-70-1.mol

Synonyms:o-nitroepoxystyrene;

Chemical Property of 2-NITROSTYRENE OXIDE)

Chemical Property:

• Vapor Pressure: 0.01mmHg at 25°C
• Melting Point: 64-65℃
• Boiling Point: 272.632oC at 760 mmHg
• Flash Point: 137.129oC
• PSA: 58.35000
• Density: 1.373g/cm3
• LogP: 2.18930

Purity/Quality:

99%min ^*data from raw suppliers

(2-NITROPHENYL)OXIRANE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-NITROSTYRENE OXIDE)

There total 12 articles about 2-NITROSTYRENE OXIDE) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2-bromo-1-(2-nitrophenyl)ethanone (6851-99-6) → (+/-)-2-(2-nitrophenyl)oxirane (39830-70-1)

Guidance literature:

With sodium tetrahydroborate; In 1,4-dioxane; water; 1.) 2 h at 5 deg C; 2.) 30 min room temperature;

Reference yield: 78.0%

2-bromo-1-(2-nitro-phenyl)-ethanol (88057-15-2) → (+/-)-2-(2-nitrophenyl)oxirane (39830-70-1)

Guidance literature:

With sodium hydroxide; In water;

DOI:10.1021/jo00177a010

Reference yield: 54.0%

2-nitro-benzaldehyde (552-89-6) + diazomethyl-trimethyl-silane (18107-18-1) → (+/-)-2-(2-nitrophenyl)oxirane (39830-70-1) + Trimethyl-[(2R,3R)-3-(2-nitro-phenyl)-oxiranyl]-silane

Guidance literature:

With triethylamine; In methanol; hexane; for 43h; Product distribution; Ambient temperature; other benzaldehydes, var. solvents, var. reaction time;

upstream raw materials:

diazomethane

2-nitro-benzaldehyde

2-bromo-1-(2-nitro-phenyl)-ethanol

diazomethyl-trimethyl-silane

Downstream raw materials:

2-chloro-1-(2-nitro-phenyl)-ethanol

α-hydroxy o-nitrosoacetophenone

2-nitro-benzeneethanol

2-Isopropylamino-1-(2-nitro-phenyl)-ethanol

Refernces

• 1、 Zhang, Jinhao,Jing, Nannan,Fan, Xinli,Tang, Xinjing. "Photoregulation of Gene Expression with Amantadine-Modified Caged siRNAs through Host–Guest Interactions". supporting information. p. 14002 - 14010. Retrieved 2020/10/02.
• 2、 Wang, Yen-Chih,Distefano, Mark D.. "Solid-phase synthesis of C-terminal peptide libraries for studying the specificity of enzymatic protein prenylation". supporting information; experimental part. p. 8228 - 8230. Retrieved 2012/09/22.