2-Furan-2-yl-4,5-dihydro-1H-imidazole

Base Information

• Chemical Name: 2-Furan-2-yl-4,5-dihydro-1H-imidazole
• CAS No.: 40029-93-4
• Molecular Formula: C7H8N2O
• Molecular Weight: 136.153
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID40357040
• Nikkaji Number: J1.293.328B
• Wikidata: Q82136732
• ChEMBL ID: CHEMBL14410
• Mol file: 40029-93-4.mol

Synonyms:2-Furan-2-yl-4,5-dihydro-1H-imidazole;2-(furan-2-yl)-4,5-dihydro-1H-imidazole;40029-93-4;CHEMBL14410;2-(2-furyl)-4,5-dihydro-1H-imidazole;2-(2-furyl)imidazoline;DTXSID40357040;HMS1698J05;BDBM50138501;AKOS000301450;PD180470;CS-0364792;A912195

Chemical Property of 2-Furan-2-yl-4,5-dihydro-1H-imidazole

Chemical Property:

• PSA: 37.53000
• LogP: 0.39380
• XLogP3: 0.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 136.063662883
• Heavy Atom Count: 10
• Complexity: 156

Purity/Quality:

97% ^*data from raw suppliers

2-Furan-2-yl-4,5-dihydro-1H-imidazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CN=C(N1)C2=CC=CO2

Technology Process of 2-Furan-2-yl-4,5-dihydro-1H-imidazole

There total 13 articles about 2-Furan-2-yl-4,5-dihydro-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

furfural (98-01-1) + ethylenediamine (107-15-3,85404-18-8) → 2-(2-furyl)-4,5-dihydro-1H-imidazole (40029-93-4)

Guidance literature:

With N-Bromosuccinimide; In dichloromethane; at 0 - 20 ℃;

DOI:10.2174/1570178611310040002

Reference yield: 92.0%

2-(2-furyl)-3,4,4-trimethyloxazolinium iodide (139214-99-6) + ethylenediamine (107-15-3,85404-18-8) → 2-(2-furyl)-4,5-dihydro-1H-imidazole (40029-93-4)

Guidance literature:

In acetonitrile; for 10h; Heating;

DOI:10.1016/S0040-4020(01)80726-2

Reference yield: 87.0%

2-(2-furyl)-4,5-dihydro-4,4-dimethyl-1,3-oxazole (83286-30-0) → 2-(2-furyl)-4,5-dihydro-1H-imidazole (40029-93-4)

Guidance literature:

for 10h; Heating;

DOI:10.1016/S0040-4020(01)80726-2

upstream raw materials:

2-(2-furyl)-3,4,4-trimethyloxazolinium iodide

ethylenediamine

2-(2-furyl)-4,5-dihydro-4,4-dimethyl-1,3-oxazole

2-furancarbonitrile

Downstream raw materials:

α,α-diphenyl-2-<(4,5-dihydroimidazol-2-yl)furan>-3-methanol

2-(2-furyl)imidazole

C₁₄H₁₂N₂O₃S

C₁₄H₁₄N₂O₃S