1-(3-Bromo-prop-1-ynyl)-4-fluoro-benzene

Base Information

Chemical Name:1-(3-Bromo-prop-1-ynyl)-4-fluoro-benzene
CAS No.:40274-29-1
Molecular Formula:C9H6BrF
Molecular Weight:213.049
Hs Code.:
European Community (EC) Number:848-764-1
Mol file:40274-29-1.mol

Synonyms:1-(3-bromo-prop-1-ynyl)-4-fluoro-benzene;40274-29-1;1-(3-Bromoprop-1-yn-1-yl)-4-fluorobenzene;1-(3-bromoprop-1-ynyl)-4-fluorobenzene;1-(3-bromoprop-1-ynyl)-4-fluoro-benzene;SCHEMBL104471;PUSYURWHOHXATJ-UHFFFAOYSA-N;CS-0131525;E81555;EN300-319771;A1-14190

Suppliers and Price of 1-(3-Bromo-prop-1-ynyl)-4-fluoro-benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 1-(3-Bromo-prop-1-ynyl)-4-fluoro-benzene

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:211.96369
Heavy Atom Count:11
Complexity:169

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1C#CCBr)F

Technology Process of 1-(3-Bromo-prop-1-ynyl)-4-fluoro-benzene

There total 4 articles about 1-(3-Bromo-prop-1-ynyl)-4-fluoro-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 80151-28-6
3-(4-fluoro-phenyl)-prop-2-yn-1-ol

: 40274-29-1
1-(3-bromoprop-1-yn-1-yl)-4-fluorobenzene

Guidance literature:: With carbon tetrabromide; triphenylphosphine; In tetrahydrofuran; at 20 ℃;

Reference yield:

: 227954-23-6
methanesulfonic acid 3-(4-fluorophenyl)prop-2-ynyl ester

: 40274-29-1
1-(3-bromoprop-1-yn-1-yl)-4-fluorobenzene

Guidance literature:: With lithium bromide; In tetrahydrofuran; at 20 ℃; for 2h; Inert atmosphere;

Reference yield:

: 352-34-1
4-fluoro-1-iodobenzene

: 40274-29-1
1-(3-bromoprop-1-yn-1-yl)-4-fluorobenzene

Guidance literature:: Multi-step reaction with 2 steps

1: diethylamine / dichlorobis(triphenylphosphine)palladium(II), copper(I) iodide / 5 h / Ambient temperature

2: PBr₃, pyridine / diethyl ether / 2.5 h / Ambient temperature

With pyridine; phosphorus tribromide; diethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In diethyl ether;
DOI:10.1021/jm9706168