Diethyl 4,5-dihydroisoxazole-3,5-dicarboxylate

Base Information

Chemical Name:Diethyl 4,5-dihydroisoxazole-3,5-dicarboxylate
CAS No.:40435-26-5
Molecular Formula:C₉H₁₃NO₅
Molecular Weight:215.206
Hs Code.:
DSSTox Substance ID:DTXSID101226589
Nikkaji Number:J1.200.027H
Mol file:40435-26-5.mol

Synonyms:diethyl 4,5-dihydroisoxazole-3,5-dicarboxylate;40435-26-5;DTXSID101226589;diethyl4,5-dihydroisoxazole-3,5-dicarboxylate;2-Isoxazoline-3,5-dicarboxylic acid diethyl ester;A914140;3,5-Diethyl 4,5-dihydro-3,5-isoxazoledicarboxylate;4,5-Dihydro-isoxazole-3,5-dicarboxylic acid diethyl ester

Suppliers and Price of Diethyl 4,5-dihydroisoxazole-3,5-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Diethyl4,5-dihydroisoxazole-3,5-dicarboxylate 97%
10g
$ 1935.00

Crysdot
Diethyl4,5-dihydroisoxazole-3,5-dicarboxylate 97%
5g
$ 1439.00

Crysdot
Diethyl4,5-dihydroisoxazole-3,5-dicarboxylate 97%
1g
$ 743.00

Total 2 raw suppliers

Chemical Property of Diethyl 4,5-dihydroisoxazole-3,5-dicarboxylate

Chemical Property:

PSA：74.19000
LogP:-0.30690
XLogP3:0.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:215.07937252
Heavy Atom Count:15
Complexity:286

Purity/Quality:

97% ^*data from raw suppliers

Diethyl4,5-dihydroisoxazole-3,5-dicarboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C1CC(=NO1)C(=O)OCC

Technology Process of Diethyl 4,5-dihydroisoxazole-3,5-dicarboxylate

There total 10 articles about Diethyl 4,5-dihydroisoxazole-3,5-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.2%

: 14337-43-0
ethyl 2-chloro-2-(hydroxyimino)acetate

: 140-88-5,9003-32-1
ethyl acrylate

: 40435-26-5
diethyl 4,5-dihydroisoxazole-3,5-dicarboxylate

Guidance literature:: With triethylamine; In diethyl ether; for 5h;
DOI:10.1007/BF00811865

Reference yield: 91.0%

: 51026-98-3
ethyl 2-nitro-3-oxobutyrate

: 140-88-5,9003-32-1
ethyl acrylate

: 40435-26-5
diethyl 4,5-dihydroisoxazole-3,5-dicarboxylate

Guidance literature:: With sulfuric acid; In acetic anhydride; acetic acid; at 20 ℃; for 3h;
DOI:10.1007/BF00699144

Reference yield: 85.0%

: 623-33-6
glycine ethyl ester hydrochloride

: 140-88-5,9003-32-1
ethyl acrylate

: 40435-26-5
diethyl 4,5-dihydroisoxazole-3,5-dicarboxylate

Guidance literature:: With tert.-butylnitrite; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; sodium hydrogencarbonate; zinc dibromide; In tert-butyl methyl ether; at 20 ℃; for 24h; Schlenk technique; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.joc.0c02281