4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]- (2S,5R,6R)-, phenylmethyl ester, 4-oxide

Base Information

Chemical Name:4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]- (2S,5R,6R)-, phenylmethyl ester, 4-oxide
CAS No.:4052-68-0
Molecular Formula:C23H24N2O5S
Molecular Weight:440.52
Hs Code.:
Mol file:4052-68-0.mol

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,
3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]- (2S,5R,6R)-, phenylmethyl
ester, 4-oxide

Synonyms:

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Chemical Property of 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]- (2S,5R,6R)-, phenylmethyl ester, 4-oxide

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Technology Process of 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]- (2S,5R,6R)-, phenylmethyl ester, 4-oxide

There total 4 articles about 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]- (2S,5R,6R)-, phenylmethyl ester, 4-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1254-56-4
benzyl (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

: 4052-68-0
1ξ-oxo-6β-(2-phenyl-acetylamino)-1λ⁴-penicillanic acid benzyl ester

Guidance literature:: With sodium periodate; In 1,4-dioxane;
DOI:10.1021/jo01051a061

Reference yield:

: 113-98-4
Penicillin G potassium

: 4052-68-0
1ξ-oxo-6β-(2-phenyl-acetylamino)-1λ⁴-penicillanic acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: dimethylformamide / Ambient temperature

2: NaIO₄ / dioxane

With sodium periodate; In 1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1021/jo01051a061

Reference yield:

: 100-39-0
benzyl bromide

: 4052-68-0
1ξ-oxo-6β-(2-phenyl-acetylamino)-1λ⁴-penicillanic acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: dimethylformamide / Ambient temperature

2: NaIO₄ / dioxane

With sodium periodate; In 1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1021/jo01051a061