3-Chloro-4-[3-(trifluoromethyl)phenoxy]aniline

Base Information

Chemical Name:3-Chloro-4-[3-(trifluoromethyl)phenoxy]aniline
CAS No.:40718-14-7
Molecular Formula:C13H9ClF3NO
Molecular Weight:287.669
Hs Code.:
DSSTox Substance ID:DTXSID401228453
Nikkaji Number:J2.866.958E
Mol file:40718-14-7.mol

Synonyms:40718-14-7;3-chloro-4-[3-(trifluoromethyl)phenoxy]aniline;3-Chloro-4-(3-trifluoromethyl-phenoxy)-phenylamine;Benzenamine, 3-chloro-4-[3-(trifluoromethyl)phenoxy]-;3-chloro-4-(3-(trifluoromethyl)phenoxy)aniline;SCHEMBL2747848;DTXSID401228453;CS-M1567;STK351404;AKOS000318168;CS-14371;DB-356935;3-chloro-4-(3-trifluoromethylphenoxy)-aniline;3-Chloro-4-(3-trifluoromethylphenoxy)phenylamine;3-Chloro-4-[3-(trifluoromethyl)phenoxy]benzenamine;A1-04816

Suppliers and Price of 3-Chloro-4-[3-(trifluoromethyl)phenoxy]aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
3-Chloro-4-(3-trifluoromethylphenoxy)phenylamine
2.500g
$ 1816.00

Matrix Scientific
3-Chloro-4-(3-trifluoromethylphenoxy)phenylamine
1g
$ 1156.00

A1 Biochem Labs
3-Chloro-4-(3-trifluoromethyl-phenoxy)-phenylamine 95%
2.5 g
$ 1100.00

Total 6 raw suppliers

Chemical Property of 3-Chloro-4-[3-(trifluoromethyl)phenoxy]aniline

Chemical Property:

PSA：35.25000
LogP:5.31450
XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:287.0324761
Heavy Atom Count:19
Complexity:300

Purity/Quality:

≥95% ^*data from raw suppliers

3-Chloro-4-(3-trifluoromethylphenoxy)phenylamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)OC2=C(C=C(C=C2)N)Cl)C(F)(F)F

Technology Process of 3-Chloro-4-[3-(trifluoromethyl)phenoxy]aniline

There total 4 articles about 3-Chloro-4-[3-(trifluoromethyl)phenoxy]aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 40718-13-6
2-chloro-4-nitro-1-(3-(trifluoromethyl)phenoxy)benzene

: 40718-14-7
3-chloro-4-[3-(trifluoromethyl)phenoxy]aniline

Guidance literature:: With hydrogenchloride; iron; In ethanol; water; at 110 ℃; for 6h;
DOI:10.1016/j.bmcl.2020.127408

Reference yield:

: 350-30-1
3-chloro-4-fluoronitrobenzene

: 40718-14-7
3-chloro-4-[3-(trifluoromethyl)phenoxy]aniline

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 80 °C

2: platinum on carbon; hydrogen / ethyl acetate / 2 h / 20 °C

With platinum on carbon; hydrogen; potassium carbonate; In ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/jm2008634

Reference yield:

: 98-17-9
3-Trifluoromethylphenol

: 40718-14-7
3-chloro-4-[3-(trifluoromethyl)phenoxy]aniline

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 80 °C

2: platinum on carbon; hydrogen / ethyl acetate / 2 h / 20 °C

With platinum on carbon; hydrogen; potassium carbonate; In ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/jm2008634