(2S)-2-chloro-N-phenylpropanamide

Base Information

Chemical Name:(2S)-2-chloro-N-phenylpropanamide
CAS No.:40781-29-1
Molecular Formula:C9H10ClNO
Molecular Weight:183.637
Hs Code.:
DSSTox Substance ID:DTXSID60364337
Wikidata:Q82148243
Mol file:40781-29-1.mol

Synonyms:(2S)-2-chloro-N-phenylpropanamide;40781-29-1;DTXSID60364337

Suppliers and Price of (2S)-2-chloro-N-phenylpropanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of (2S)-2-chloro-N-phenylpropanamide

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:183.0450916
Heavy Atom Count:12
Complexity:155

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)NC1=CC=CC=C1)Cl
Isomeric SMILES:C[C@@H](C(=O)NC1=CC=CC=C1)Cl

Technology Process of (2S)-2-chloro-N-phenylpropanamide

There total 3 articles about (2S)-2-chloro-N-phenylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 29617-66-1
(S)-2-chloropropanoic acid

: 62-53-3
aniline

: 40781-29-1
(S)-(-)-N-Phenyl-2-chloropropionamide

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 10h; Inert atmosphere;
DOI:10.1002/ejoc.200900089

Reference yield:

: 62-53-3
aniline

: 535-13-7
2-chloro-propanoic acid, ethyl ester

: 40781-29-1
(S)-(-)-N-Phenyl-2-chloropropionamide

: 94347-47-4
(R)-N-Phenyl-2-chloropropionamide

Guidance literature:: yeast lipase (Candida cylindracea); In tetrachloromethane; at 60 ℃; for 48h; Yield given. Yields of byproduct given;
DOI:10.1016/S0040-4039(00)88491-9

Reference yield:

: 17639-93-9
2-chloro-propionic acid methyl ester

: 62-53-3
aniline

: 40781-29-1
(S)-(-)-N-Phenyl-2-chloropropionamide

: 94347-47-4
(R)-N-Phenyl-2-chloropropionamide

Guidance literature:: With aluminium trichloride; In toluene; Yield given. Yields of byproduct given. Title compound not separated from byproducts;