2,2-difluorooctane

Base Information

• Chemical Name: 2,2-difluorooctane
• CAS No.: 407-89-6
• Molecular Formula: C8H16F2
• Mol file: 407-89-6.mol

Synonyms:

Chemical Property of 2,2-difluorooctane

Chemical Property:

• Vapor Pressure: 4.6mmHg at 25°C

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2-difluorooctane

There total 9 articles about 2,2-difluorooctane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-2-Chlor-2-octen (57024-91-6) → 2,2-Difluor-octan (407-89-6) + 2,2-dichloro-octane (73642-95-2)

Guidance literature:

With hydrogen fluoride; at 46 ℃;

DOI:10.1021/ja01257a032

Reference yield:

n-octyne (629-05-0) → 2,2-Difluor-octan (407-89-6)

Guidance literature:

With hydrogen fluoride; acetone;

Reference yield:

hexyl-methyl-ketone (111-13-7) → 2,2-Difluor-octan (407-89-6)

Guidance literature:

With (bis-(2-methoxyethyl)amino)sulfur trufluoride; In dichloromethane;

DOI:10.1016/j.tetlet.2011.03.101

upstream raw materials:

n-octyne

(E)-2-Chlor-2-octen

diethyl ether

hydrogen fluoride

Downstream raw materials:

C₁₈H₂₄F₂O₄

Refernces

• 1、 Wu, Li-Lan,Yang, Chung-Ling,Lo, Feng-Chun,Chiang, Chih-Hsiang,Chang, Chun-Wei,Ng, Kok Yaoh,Chou, Ho-Hsuan,Hung, Huei-Ying,Chan, Sunney I.,Yu, Steve S.-F.. "Tuning the regio- and stereoselectivity of C-H activation in n-octanes by cytochrome P450 BM-3 with fluorine substituents: Evidence for interactions between a C-F bond and aromatic π systems". supporting information; experimental part. p. 4774 - 4787. Retrieved 2011/11/14.