(5S)-5-(1H-indol-3-ylmethyl)imidazolidine-2,4-dione

Base Information

Chemical Name:(5S)-5-(1H-indol-3-ylmethyl)imidazolidine-2,4-dione
CAS No.:40856-80-2
Molecular Formula:C₁₂H₁₁N₃O₂
Molecular Weight:229.238
Hs Code.:
DSSTox Substance ID:DTXSID90364345
Nikkaji Number:J1.482.861C
Wikidata:Q27461330
ChEMBL ID:CHEMBL1958130
Mol file:40856-80-2.mol

Synonyms:40856-80-2;(5S)-5-(1H-indol-3-ylmethyl)imidazolidine-2,4-dione;(S)-5-((1H-Indol-3-yl)methyl)imidazolidine-2,4-dione;4d1a;CHEMBL1958130;DTXSID90364345;L-5-(3'-indolylmethylene)-hydantoin;(S)-5-(3'-indolylmethylene)-hydantoin;(5S)-5-(1H-Indole-3-ylmethyl)hydantoin;EN300-7431207;Q27461330;Z3031664931;(5S)-5-[(1H-indol-3-yl)methyl]imidazolidine-2,4-dione;I5H

Suppliers and Price of (5S)-5-(1H-indol-3-ylmethyl)imidazolidine-2,4-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
(5S)-5-(1H-Indol-3-ylmethyl)imidazolidine-2,4-dione
2.5g
$ 892.00

AK Scientific
(5S)-5-(1H-Indol-3-ylmethyl)imidazolidine-2,4-dione
250mg
$ 248.00

Total 3 raw suppliers

Chemical Property of (5S)-5-(1H-indol-3-ylmethyl)imidazolidine-2,4-dione

Chemical Property:

PSA：80.97000
LogP:0.83430
XLogP3:1.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:229.085126602
Heavy Atom Count:17
Complexity:345

Purity/Quality:

99% ^*data from raw suppliers

(5S)-5-(1H-Indol-3-ylmethyl)imidazolidine-2,4-dione ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=CN2)CC3C(=O)NC(=O)N3
Isomeric SMILES:C1=CC=C2C(=C1)C(=CN2)C[C@H]3C(=O)NC(=O)N3
Uses (5S)-5-(1H-Indol-3-ylmethyl)-2,4-Imidazolidinedione is used in the synthesis of Tryptophan (CAS# 73-22-3). It can also be in ligand recognition mechanisms for membrane transport proteins.

Technology Process of (5S)-5-(1H-indol-3-ylmethyl)imidazolidine-2,4-dione

There total 4 articles about (5S)-5-(1H-indol-3-ylmethyl)imidazolidine-2,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 917-61-3
sodium isocyanate

: 73-22-3,27732-43-0,80206-30-0,27813-82-7
L-Tryptophan

: 40856-80-2
L-tryptophan hydantoin

Guidance literature:: sodium isocyanate; L-Tryptophan; In water; at 50 ℃;

With hydrogenchloride; In water; Reflux;
DOI:10.1021/jm201243p

Reference yield: 77.0%

: 590-28-3
potassium cyanate

: 7524-52-9,26988-71-6,5619-09-0,14907-27-8,41222-70-2,67557-19-1,109492-62-8
(S)-tryptophan methyl ester hydrochloride

: 40856-80-2
L-tryptophan hydantoin

Guidance literature:: potassium cyanate; (S)-tryptophan methyl ester hydrochloride; In water; Milling; Green chemistry;

With caesium carbonate; triethylamine; In water; Green chemistry;
DOI:10.1021/jo5017629