Benzeneacetyl chloride, a-methyl-a-phenyl-

Base Information

• Chemical Name: Benzeneacetyl chloride, a-methyl-a-phenyl-
• CAS No.: 40997-78-2
• Molecular Formula: C15H13ClO
• Molecular Weight: 244.721
• Mol file: 40997-78-2.mol

Synonyms:

Chemical Property of Benzeneacetyl chloride, a-methyl-a-phenyl-

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzeneacetyl chloride, a-methyl-a-phenyl-

There total 10 articles about Benzeneacetyl chloride, a-methyl-a-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2,2-diphenylpropanoic acid (5558-66-7) → 2,2-diphenylpropionyl chloride (40997-78-2)

Guidance literature:

With thionyl chloride; N,N-dimethyl-formamide; for 1h; Ambient temperature;

DOI:10.1002/jlac.199719970122

Reference yield:

2,2-diphenylpropanoic acid (5558-66-7) → carbon monoxide (201230-82-2) + 2,2-diphenylpropionyl chloride (40997-78-2) + 1,1-diphenylethylium (16805-85-9)

Guidance literature:

With tungsten(VI) chloride; In dichloromethane-d2; at 20 ℃; for 2h; Inert atmosphere; Schlenk technique;

DOI:10.1039/c8dt04416c

Reference yield:

2,2-diphenylpropanal (22875-82-7) → 2,2-diphenylpropionyl chloride (40997-78-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 65 percent / KMnO₄, NaHCO₃ / H₂O / Heating

2: SOCl₂ / 1 h / Heating

With potassium permanganate; thionyl chloride; sodium hydrogencarbonate; In water;

DOI:10.1021/jm00385a008

upstream raw materials:

2,2-diphenylpropanoic acid

2,2-diphenylacetic acid

Diphenylacetonitrile

2,2-diphenylpropanal

Downstream raw materials:

1-(2,2-diphenyl-propionyl)-4-methyl-piperazine

2,2-diphenyl-peroxypropionic acid tert-butyl ester

(+)-azaprophen

azaprophen