Acetylresveratrol

Base Information

• Chemical Name: Acetylresveratrol
• CAS No.: 411233-11-9
• Molecular Formula: C16H14O4
• Molecular Weight: 270.285
• DSSTox Substance ID: DTXSID70194066
• Mol file: 411233-11-9.mol

Synonyms:Acetylresveratrol;UNII-T07O870429;4'-O-acetyl-resveratrol;DTXSID70194066;MEMZFJTYLFBJEC-UHFFFAOYSA-N;4'-acetoxy-3,5-dihydroxystilbene

Chemical Property of Acetylresveratrol

Chemical Property:

• PSA: 66.76000
• LogP: 3.19350
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 270.08920892
• Heavy Atom Count: 20
• Complexity: 334

Purity/Quality:

98% ^*data from raw suppliers

ACETIC ACID-4-[2-(3,5-DIHYDROXY-PHENYL)-VINYL]-PHENYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(=O)OC1=CC=C(C=C1)C=CC2=CC(=CC(=C2)O)O

Technology Process of Acetylresveratrol

There total 17 articles about Acetylresveratrol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

vinyl acetate (108-05-4,9003-20-7) + (E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol (501-36-0) → 4'-Acetylresveratrol (411233-11-9)

Guidance literature:

With novozyme 435 from Candida antarctica; In tert-Amyl alcohol; at 40 ℃; for 120h; regioselective reaction; Enzymatic reaction;

DOI:10.1042/BSR20171712

Reference yield: 85.0%

(E)-4-(3,5-bis(benzyloxy)styryl)phenyl acetate (1432450-00-4) → 4'-Acetylresveratrol (411233-11-9)

Guidance literature:

With dimethylsulfide; boron trifluoride diethyl etherate; In dichloromethane; for 20h; Inert atmosphere;

DOI:10.1016/j.bmcl.2013.03.046

Reference yield: 80.0%

(E)-1-(4'-acetoxyphenyl)-2-(3,5-dimethoxyphenyl)ethene (18259-14-8,63366-83-6) → 4'-Acetylresveratrol (411233-11-9)

Guidance literature:

With boron trichloride; tetra-(n-butyl)ammonium iodide; In dichloromethane; at 0 - 20 ℃; for 2h;

DOI:10.1016/j.tetlet.2008.07.087

upstream raw materials:

vinyl acetate

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

acetic anhydride

p-acetoxystyrene

Downstream raw materials:

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

(E)-4-(3,5-bis((triisopropylsilyl)oxy)styryl)phenyl acetate

(E)-4-(3,5-bis((triisopropylsilyl)oxy)styryl)phenol

4-[(E)-3,5-bis(triisopropylsilyloxy)styryl]phenyl (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoate