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Resveratrol CAS 501-36-0 IN Stock 3,4',5-Trihydroxy-trans-stilbene 501-36-0
Cas No: 501-36-0
USD $ 3.5-5.0 / Kiloliter 5 Kiloliter 3000 Metric Ton/Month Chemwill Asia Co., Ltd. Contact Supplier
Best price trans resveratrol powder 99% resveratrol
Cas No: 501-36-0
USD $ 220.0-240.0 / Kilogram 1 Kilogram 10 Metric Ton/Month Shaanxi Greenyo Biotech Co., Ltd. Contact Supplier
High quality Resveratrol in stock
Cas No: 501-36-0
USD $ 0.1-0.2 / Kilogram 1 Kilogram 1000 Kilogram/Month Binbo Biological Co., Ltd Contact Supplier
Resveratrol/high quality Polygonum cuspidatum extract Resveratrol powder 98%
Cas No: 501-36-0
USD $ 200.0-200.0 / Gram 1 Gram 1 Metric Ton/Day DB BIOTECH CO., LTD Contact Supplier
Resveratrol/Polygonum cuspidatum Extract/CAS:501-36-0
Cas No: 501-36-0
No Data 10 Gram 3 Metric Ton/Week Qingdao Beluga Import and Export Co., LTD Contact Supplier
Resveratrol with high quality
Cas No: 501-36-0
USD $ 80.0-100.0 / Kilogram 1 Kilogram 100 Kilogram/Day Zibo Hangyu Import&Export Co., Ltd Contact Supplier
Resveratrol
Cas No: 501-36-0
No Data No Data No Data CHANGZHOU HANGYU PHARMACEUTICAL TECHNOLOGY CO., LTD Contact Supplier
Pure Natrual Hight purity 99% Resveratrol trans resveratrol
Cas No: 501-36-0
USD $ 26.0-26.0 / Kilogram 1 Kilogram 1000 Kilogram/Month Greenutra Resource Inc Contact Supplier
Bulk price High quality natural giant knot weed extract resveratrol 98% powder
Cas No: 501-36-0
USD $ 100.0-278.0 / Kilogram 1 Kilogram 10000 Kilogram/Month Xi'an Quanao Biotech Co., Ltd. Contact Supplier
polygonum cuspidatum extract resveratrol 98%
Cas No: 501-36-0
USD $ 257.0-257.0 / Kilogram 1 Kilogram 1 Metric Ton/Month Changsha Staherb Natural Ingredients Co.,Ltd Contact Supplier

501-36-0 Usage

Possible Side effects

Little is known about the safety of long-term or high dose use of resveratrol. Since resveratrol might act like estrogen, some medical experts recommend that people with hormone-sensitive cancers (condition such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids), pregnant women, and children avoid taking resveratrol. In addition, resveratrol could interact with blood thinners like warfarin, aspirin, and ibuprofen by slow blood clotting, which may increase the risk of bleeding in people with bleeding disorders. According to one study, high-dose resveratrol supplementation was associated with fever, reduced blood cells, and decreased blood pressure. There is some concern that high doses of resveratrol supplements could lead to kidney problems in some people.

Solubility

Resveratrol is a kinds of natural antioxidants that presents in grapes, red wine, mulberries, peanuts and polygonum cuspidatum. It is polyphenols. It is soluble in organic solvents but insoluble in water. Its dissolved order in organic solvents is: acetone > ethanol> methanol> ethyl acetate> ether> chloroform.

Pharmacological effects

Resveratrol is not only the chemopreventive agents of neoplastic diseases, but also the chemopreventive agents to reduce platelet aggregation and prevent and treat atherosclerosis, cardiovascular and cerebrovascular disease. In the 1990s, studies of science and technology workers on resveratrol have advanced, and reveal its pharmacological effects. It can inhibit normal platelet aggregation, prevent myocardial cram, cerebral embolism. It has a protective effect on cardiac hypoxia, restore decline of cardiac output which is caused by burn or hemorrhagic shock, and can expand arteries and improve microcirculation. In 1998, United States Al.Mindell listed resveratrol as one of “the 100 most popular and effective anti-aging substance” when he compiled the anti-aging Scripture. Peanut oil, peanut butter and other foods rich in resveratrol will be the new fashion of nutrition and health in the 21st century. Resveratrol is the chemopreventive agents of neoplastic diseases, but also the chemopreventive agents to reduce platelet aggregation and prevent and treat atherosclerosis, cardiovascular and cerebrovascular disease. Resveratrol shows some inhibitory effect on staphylococcus aureus, the card he bacteria, escherichia coli, pseudomonas aeruginosa, and has a stronger inhibitory effect on the orphan virus, herpes simplex virus, and enteroviruses, coxsackie a, b groups.

The synthetic method of resveratrol

Resveratrol is an inhibitor of many oxidative metabolism enzymes of aromatic carcinogens. It is named as the natural chemopreventive agents of cardiovascular and cerebrovascular diseases and cancer. Many studies have shown that resveratrol also has many functions, such as anti-mutagenic activity, protecting cell toxicity induced by the oxidation of lipoprotein, inhibiting tumor cell reproduction, and so on. Human separated resveratrol from the root of veratrum grandiflorum for the first time in 1940. Researchers currently has found resveratrol from at least 21 families and 31 genera of 72 species of plants, such as grape vine genus, vitis snake, legumes arachis, cassia, sophora, polygonum, and so on. Because of the low concentration of resveratrol in the plant and the high extraction cost, using chemical, biological, genetic engineering and other methods to obtain resveratrol has become an indispensable means for its development process. The roadmap to synthesis resveratrol is as follows: 3,5-dihydroxybenzoic acid (3) forms 3,5-dihydroxybenzoic acid methyl ester (4) by esterification reaction. Choose methyl ether as phenolic hydroxyl-protecting groups. (4) reacts with dimethyl sulfate to get 3,5-di-methoxybenzoate (5). (5) generates the corresponding benzene methanol (6) after reduction, and forms 3, 5-dimethoxy benzyl bromide (7) through further bromination. Then diethyl (3,5-dimethoxy benzyl) phosphonate (8) can be get by roman abramovich's reaction. (8) reacts with p-anisaldehyde to form the key intermediate 3,4,5-trimethoxy-trans-stilbene (9) via Wittig-Honer reaction. Finally, methyl can be removed by freshly prepared aluminum triiodide. Then the aimed product resveratrol can be separated by thin layer chromatography.

Contents determination method

C18 column, mobile phase consisted of acetonitrile and water (volume ratio 30: 70), and UV detection at 30 6nm are used to detect. The results show that if the concentration of resveratrol is in 10~250 μg/mL, concentration and peak area show a good linear relationship (r = 0.9999); the recovery is 925% to 1026%; the lowest detectable concentration is 0.6mg/g. The flow rate can be adjusted to detect the enzymatic conversion of polydatin and resveratrol at the same time.

Chemical Properties

Off-White to Tan Powder

Uses

raw material for Tamiflu; Oseltamivir

Definition

ChEBI: A resveratrol in which the double bond has E configuration.

description

Resveratrol is a natural antioxidant. It can reduce blood viscosity, inhibit platelet aggregation and vasodilation, keep the blood flowing and prevent the occurrence and development of cancer. It has the function to prevent and treat atherosclerosis, coronary heart disease, ischemic heart disease and high blood cholesterol. It has an effect on suppressing tumor. Resveratrol also has estrogen-like effects that can be used to treat breast cancer and other diseases. It can retard aging and prevent cancer. Red grape skins, red wine and grape juice have high concentrations of resveratrol. Studies have shown that the integrity of the chromosomes will be destroyed as the human aging. But resveratrol can activate proteins that can repair chromosome, thus delaying aging. Resveratrol is a polyphenolic phytoalexin. It is also classified as a stilbenoid, a derivate of stilbene, and is produced in plants with the help of the enzyme stilbene synthase. The levels of resveratrol found in food varies greatly. Red wine contains between 0. 2 and 5. 8 mg/L depending on the grape variety, while white wine has much less. The reason for this difference is that red wine is fermented with grape skins, allowing the wine to absorb the resveratrol, whereas white wine is fermented after the skin has been removed. Resveratrol is a very effective anti-oxidant with 95% efficiency in preventing lipid peroxidation as compared with 37% for Vitamin C or 65% for Vitamin E. It has very strong peroxyl radical scavenging abilities, more than gallic and ellagic acids and epicatechins. Resveratrol has been shown to protect against UVB mediated skin damage in mice by boosting anti-oxidant defenses, and it has been shown to help alleviate skin wounds. Resveratrol is effective against photoaging due, in part, to its anti-oxidant properties, and is recommended for use in pre- or post-sun exposure products. Resveratrol can pass through the stratum corneum to be found in the dermis and epidermis. It has been shown to preserve dermal collagen, and may be effective in enhancing glycosaminoglycans, which enhance tissue hydration. It has been shown to stimulate skin’s cellular renewal, and help increase skin's thickness. And it has been shown to inhibit tyrosinase, which indicates its use for reducing hyperpigmentation.

Biological Activity

A phytoestrogen with antitumor, antioxidant, antiplatelet, anti-inflammatory and antifungal effects. Inhibits cytochrome P450 1A1 (IC 50 = 23 μ M) and displays mixed agonist/antagonist actions at ER α and ER β estrogen receptors. Converted into the anticancer agent piceatannol (4-[(1E)-2-(3,5-Dihydroxyphenyl)ethenyl]-1,2-benzenediol ) by cytochrome P450 1B1

Resveratrol Extraction

Polygonum cuspidatum is the rhizome of polygonaceae polygonum cuspidatum. Polygonum cuspidatum rhizome contains free anthraquinone and anthraquinone glycosides, whch mainly are emodin ether, rhubarb phenol, anthracene glycosides A and B, etc. It also contains resveratrol glycosides, polydatin, protocatechuic acid, dextrose catechin, tree anthrone-8-glucosidecassia, β-sitosterol glucoside and glucose, rhamnose, ginger candy, amino acids, tannin and copper, iron, manganese, zinc, potassium and potassium salts, etc. Figure 1 is Polygonum cuspidatum plant Resveratrol (Res) is a non-flavonoid polyphenol compound. It is considered as a phytoalexin, which is generated when the plant is attacked by pathogenic, or in the poor environment. It is mainly found in grapes, giant knotweed, peanuts, mulberry, pine, Gnetum, Korea Huaifrom 12 families and 31 genera of 72 species of plants. Extraction of the natural plant: polygonum cuspidatum is used as raw material, extracted, extracted resveratrol crude, and then purified. Crude extraction technologies include organic solvent extraction method, the new method of alkaline extraction and enzymatic extraction method. New methods like microwave-assisted extraction, CO2 supercritical extraction and ultrasonic extraction are also applied. The main purpose of purification is to extract cis-resveratrol and trans-resveratrol and polydatin from raw resveratrol to obtain trans-resveratrol. Common methods of purification are chromatography, silica gel column chromatography, thin-layer chromatography, high performance liquid chromatography and the like. Resveratrol had significant antioxidant activity on animal fats. Sample of 240mg/kg shows the strongest antioxidant activity during the three samples whose concentration of resveratrol is respectively 120 mg/kg, 240mg/kg, 360mg/kg. In antioxidant tests on lard, the antioxidant effect of resveratrol is stronger than polyphenols with same concentration.

Uses

Minor constituent of wine, correlated with serum lipid reduction and inhibition of platelet aggregation. Resveratrol is a specific inhibitor of COX-1, and it also inhibits the hydroperoxidase activity of COX-1. It has been shown to inhibit events associated with tumor initiation, promotion and progression.

Resveratrol Benefits and ralting biological activities

Much of the research pointing to the benefits have been laboratory or animal-based studies. So far, research on resveratrol's effectiveness in humans has yielded mixed results. Anti-Aging and Anti-Cancer Effects Effects on biotransformation enzymes Inhibition of proliferation and induction of apoptosis Inhibition of tumor invasion and angiogenesis Anti-inflammatory effects Protects Cardiovascular Health Inhibition of vascular cell adhesion molecule (VCAM) expression Inhibition of vascular smooth muscle cell (VSMC) proliferation Stimulation of endolethelial nitric oxide synthase (eNOS) activity Inhibition of platelet activiation and aggregation Helps Protect the Brain and Cognitive/Mental Health Stimulation of neurogenesis and microvessel formation Stimulation of β-amyloid peptide clearance Inhibition of neuroinflammation Reduction of oxidative stress

Uses

Resveratrol can prevent the oxidation of low density lipoprotein, and has the potential effect on preventing cardiovascular disease, cancer, antivirus and immune regulation. Its main role is antioxidant properties. Cardiovascular drugs. It can reduce hematic fat and prevent heart disease. It also has the effect on AIDS. Antioxidants and the activity in anti-inflammatory, antithrombotic, anti-cancer, anti-cancer, anti hyperlipidemia and antibacterial. Anti-aging, regulating blood lipid, cardiovascular protection, anti-hepatitis. Resveratrol is a phytoalexin produced naturally by several plants with anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects.

Synthesis Reference(s)

Tetrahedron Letters, 43, p. 597, 2002 DOI: 10.1016/S0040-4039(01)02227-4

resveratrol sources plants

Resveratrol is anthraquinone terpenoids. It mainly comes from rhizome extract of polygonum cuspidatum. Polygonum cuspidatum: Shrubby perennial herb, up to 1 meter or more. Rhizome lying underground, wood brown, section significantly. Stems erect and cylindrical, surface glabrous, scattered with most red spots, hollow. Leaves alternate, broadly ovate to nearly circular, long 7-12cm, width 5-9cm, apex mucronate, base rounded or cuneate; petiole 1-1.5cm sheath care quality, brown, early fall. Flowering is from July to September, and fruiting from September to October. Spring and autumn can be excavated, cut and dried. Polygonum cuspidatum is born in the valley, creek or shore.

Anticancer Research

Resveratrol is a stilbinoid, found in the skin of grapes, peanuts, berries, and otherfruits. The cytotoxic effect of resveratrol is mediated via the inhibition of severaltranscription factors; upregulation of caspases, Bax, and p53; and downregulationof survivin, cyclins, and Bcl-2. Increase in Bax/Bcl-2 ratio and upregulation ofcaspases lead to apoptosis. The beneficial effects of resveratrol against cancer havebeen shown in all the stages of cancer including carcinogenesis, initiation,promotion, and progression. It could inhibit Wnt target gene expression in normalcolonic mucosa of the colorectal cancer patients. It increases the caspase-3 inmalignant hepatic tissue and induces anticarcinogenic effects in humangastrointestinal tract (Hosseini and Ghorbani 2015). It has the ability to inhibit thedevelopment of DMBA-induced phenoblastic lesions in the mammary gland organculture (MMOC) model of carcinogenesis and in two-stage full-term mouse model(Balunas and Kinghorn 2005). It prevents carcinogenesis by upregulating Bax andp53 proteins and downregulating NF-κB, COX-2, AP-1, cyclin-dependent kinases,hypoxia-induced factor 1α (HIF-1α), cyclins, MMPs, cytokines, and Bcl-2 proteins(Singh et al. 2016b). It plays a pivotal role in preventing the initiation, promotion,and progression of cancer by inducing phase II drug metabolizing enzymes, bymediating anti-inflammatory effects and inhibiting COX and hydroperoxidasefunctions, and by inducing cell differentiation, respectively, in human promyelocyticleukemic cells (Jang et al. 1997; Aggarwal et al. 2004).Resveratrol, a noteworthy polyphenol occurring in different plants such as grapesand peanuts, has appeared to be required in cell reinforcement, anti-proliferative,anti-inflammatory, and chemopreventive activities. Various potential medicaladvantages, including decreased danger of malignancy and coronary illness, arebelieved to be related to the utilization of resveratrol. It can successfully and proficientlyrepress endothelial cell multiplication and migration, with little cell toxicityin the HUVEC and ARPE19 lines (Cao et al. 2010). Also, there have been perceptionsof inhibitory consequences for smooth muscle cell migration (Venkatesanet al. 2009) and tumor necrosis factor-alpha-incited monocyte adhesion and migration(Kim et al. 2007). As of late, it was recognized that the restraint of PDGF-BB-actuatedcell migration by resveratrol and the particular inhibitors PDGF-R, PI3K,MEK, or p38 in wound healing test agreed with diminished enactment of PDGFBB-incited PDGFR-β, PI3K/Akt, ERK, and p38 phosphory-lation in Western blotinvestigation, recommending that resveratrol hinders cell migration through theinhibition of PI3K/Akt, PDGFR-β, and MAPK cascade (Chan et al. 2013).
InChI:InChI=1/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+

501-36-0 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
TCI America (R0071)  Resveratrol  >99.0%(GC) 501-36-0 1g 140.00CNY Detail
TCI America (R0071)  Resveratrol  >99.0%(GC) 501-36-0 5g 440.00CNY Detail
TCI America (R0071)  Resveratrol  >99.0%(GC) 501-36-0 25g 1,350.00CNY Detail
Sigma-Aldrich (76511)  Resveratrol  certified reference material, TraceCERT® 501-36-0 76511-100MG 5,071.95CNY Detail
Sigma-Aldrich (34092)  Resveratrol  analytical standard 501-36-0 34092-100MG 2,929.68CNY Detail
Sigma-Aldrich (Y0001194)  Resveratrol  European Pharmacopoeia (EP) Reference Standard 501-36-0 Y0001194 1,880.19CNY Detail

501-36-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name resveratrol

1.2 Other means of identification

Product number -
Other names trans-3,5,4'-trihydroxy-stilbene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:501-36-0 SDS

501-36-0Synthetic route

3,5,4'-trimethoxy-trans-stilbene
22255-22-7

3,5,4'-trimethoxy-trans-stilbene

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With boron tribromide In dichloromethane at 0 - 30℃;100%
With boron tribromide In dichloromethane at 0 - 20℃;99%
With aluminum (III) chloride; sodium sulfate; triethylamine In chlorobenzene at 0 - 115℃; for 6.5h; Inert atmosphere;98%
(E)-1-(4-(benzyloxy)phenyl)-2-(3,5-bis(benzyloxy)phenyl)-ethene
89946-06-5

(E)-1-(4-(benzyloxy)phenyl)-2-(3,5-bis(benzyloxy)phenyl)-ethene

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
Stage #1: (E)-1-(4-(benzyloxy)phenyl)-2-(3,5-bis(benzyloxy)phenyl)-ethene With aluminum (III) chloride; triethylamine In chlorobenzene at 0 - 80℃; for 10h;
Stage #2: With water In chlorobenzene at 0℃; for 2h; Product distribution / selectivity;
100%
With aluminum (III) chloride; N,N-dimethyl-aniline at 40 - 50℃;90%
With hydrogen In dichloromethane at 20℃; under 3750.38 Torr; for 5h;87%
(E)-3,5,4'-tri(benzoyloxy)styrene
710969-83-8

(E)-3,5,4'-tri(benzoyloxy)styrene

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With sodium methylate In tetrahydrofuran; methanol at 50℃; for 5h;98%
(E)-4-(3,5-bis(methoxymethoxy)styryl)phenol
1217011-33-0

(E)-4-(3,5-bis(methoxymethoxy)styryl)phenol

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With hydrogenchloride In methanol; water at 20 - 65℃; for 3h; Inert atmosphere;97%
3,5-dihydroxybenzaldehyde
26153-38-8

3,5-dihydroxybenzaldehyde

dimethyl (4-hydroxybenzyl)phosphonate
68997-88-6

dimethyl (4-hydroxybenzyl)phosphonate

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With RS004 catalyst In ethanol at 20℃; for 6h; Wittig-Horner Reaction;97%
4'-Acetylresveratrol
411233-11-9

4'-Acetylresveratrol

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With sodium hydroxide In tetrahydrofuran for 2h; Heating;95%
3,5,4'-trimethoxystilbene
22255-22-7, 94608-23-8, 63844-75-7

3,5,4'-trimethoxystilbene

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
Stage #1: 3,5,4'-trimethoxystilbene With boron tribromide In toluene at 0 - 20℃; for 2.03333h;
Stage #2: With water; sodium hydrogencarbonate In toluene at 0℃; for 0.333333h;
92%
With aluminum (III) chloride; triethylamine In chlorobenzene at 60 - 70℃; for 0.5h; Inert atmosphere;90%
Multi-step reaction with 2 steps
1: BBr3
2: diphenyl disulphide / tetrahydrofuran / Heating
View Scheme
With pyridine hydrochloride at 190 - 195℃; for 4h;
Stage #1: 3,5,4'-trimethoxystilbene With iodine In hexane for 48h; Reflux;
Stage #2: With boron tribromide In dichloromethane at 0 - 20℃; for 5h;
(E)-2,4,6-tribromo-3,5,4'-trihydroxystilbene
1399502-89-6

(E)-2,4,6-tribromo-3,5,4'-trihydroxystilbene

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With sodium sulfite In water at 60℃; for 6h; Green chemistry;90%
triacetyl-trans-resveratrol
42206-94-0

triacetyl-trans-resveratrol

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With sodium hydroxide In tetrahydrofuran88%
Stage #1: triacetyl-trans-resveratrol With potassium hydroxide In methanol for 1h; Inert atmosphere; Reflux;
Stage #2: With hydrogenchloride In methanol; water pH=2; Inert atmosphere;
79%
With sodium methylate In tetrahydrofuran; methanol
With potassium hydroxide In methanol; ethyl acetate
(E)-1-(3,5-di-isopropoxyphenyl)-2-(4-isopropoxyphenyl)ethene
587870-67-5

(E)-1-(3,5-di-isopropoxyphenyl)-2-(4-isopropoxyphenyl)ethene

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With boron trichloride In dichloromethane at -78 - -10℃;85%
C15H12O5(C2H2O)3

C15H12O5(C2H2O)3

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With 1-methyl-1H-imidazole; sodium hydrogencarbonate for 0.333333h; Heating; microwave irradiation;84%
(Z)-1-(3,5-dimethoxyphenyl)-2-(4-methoxyphenyl)ethene
94608-23-8

(Z)-1-(3,5-dimethoxyphenyl)-2-(4-methoxyphenyl)ethene

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With aluminium(III) iodide In acetonitrile at 82℃; for 3h;83.8%
With aluminium(III) iodide In acetonitrile at 82℃; for 3h;73%
pinosylvin
22139-77-1

pinosylvin

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With L234Q/I238V/G239A In dimethyl sulfoxide at 20℃; for 20h; Reagent/catalyst; Enzymatic reaction; regioselective reaction;83%
With unspecific peroxygenase from Marasmius rotula DSM-25031; dihydrogen peroxide; ascorbic acid In aq. phosphate buffer; acetone at 30℃; for 0.5h; pH=7; Enzymatic reaction; regioselective reaction;
C15H12O5
906463-95-4

C15H12O5

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With copper(l) iodide; 1,10-Phenanthroline at 180 - 190℃; Microwave irradiation; Inert atmosphere; Green chemistry;82%
5-[(1E)-2-(phenylbenzyloxy)vinyl]-1,3-cyclohexanedione

5-[(1E)-2-(phenylbenzyloxy)vinyl]-1,3-cyclohexanedione

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With 5%-palladium/activated carbon; hydrogen In acetonitrile under 2280.15 Torr; for 48h;80%
(E)-1-(3,5-bis-{[tert-butyl(dimethyl)silyl]oxy}phenyl)-2-(4-{[tert-butyl(dimethyl)silyl]oxy}phenyl)ethene
676596-85-3

(E)-1-(3,5-bis-{[tert-butyl(dimethyl)silyl]oxy}phenyl)-2-(4-{[tert-butyl(dimethyl)silyl]oxy}phenyl)ethene

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With hydrogenchloride In ethanol at 20℃; for 26h;79%
With hydrogenchloride In methanol at 20℃; for 36h;
1-(1-bromoethyl)-3,5-diacetoxybenzene
1026420-83-6

1-(1-bromoethyl)-3,5-diacetoxybenzene

4-bromophenyl acetate
1927-95-3

4-bromophenyl acetate

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
Stage #1: 1-(1-bromoethyl)-3,5-diacetoxybenzene With lithium carbonate In ISOPROPYLAMIDE at 120℃; for 2h; Inert atmosphere;
Stage #2: 4-bromophenyl acetate With potassium phosphate; palladium oximate In ISOPROPYLAMIDE at 130℃; for 19.75h; Inert atmosphere;
Stage #3: With water; potassium carbonate at 110℃; for 2.5h; Product distribution / selectivity;
77%
4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

(3,5-dihydroxybenzyl)triphenylphosphonium bromide

(3,5-dihydroxybenzyl)triphenylphosphonium bromide

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran at 80℃;75%
(E)-1-[4-(hexyloxy)phenyl]-2-(3,5-dimethoxyphenyl)ethene
190371-53-0

(E)-1-[4-(hexyloxy)phenyl]-2-(3,5-dimethoxyphenyl)ethene

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With boron tribromide In dichloromethane at 0 - 20℃; for 4h;70%
(E)-2-(4'-hydroxyphenyl)-3-(3',5'-dihydroxyphenyl)acrylic acid

(E)-2-(4'-hydroxyphenyl)-3-(3',5'-dihydroxyphenyl)acrylic acid

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With quinoline; copper at 200℃; for 3h; Inert atmosphere; diastereoselective reaction;60.8%
With quinoline; copper
2-(3,5-dihydroxyphenyl)acetic acid
4670-09-1

2-(3,5-dihydroxyphenyl)acetic acid

4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With piperidine; 1-methyl-1H-imidazole In various solvent(s) at 160℃; for 0.166667h; microwave irradiation;51%
5-iodoresorcinol
64339-43-1

5-iodoresorcinol

4-Vinylphenol
2628-17-3

4-Vinylphenol

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With triethanolamine; palladium diacetate at 100℃; for 24h; Mizoroki-Heck reaction; Inert atmosphere;41.4%
With triethanolamine; palladium diacetate at 100℃; for 24h; Mizoroki-Heck reaction; Inert atmosphere; stereoselective reaction;41.4%
With triethanolamine; palladium diacetate at 100℃; for 24h; Heck Reaction; Inert atmosphere;
5-[(E)-2-(4-methoxyphenyl)vinyl]benzene-1,3-diol
65728-21-4, 33626-08-3

5-[(E)-2-(4-methoxyphenyl)vinyl]benzene-1,3-diol

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With pyridine hydrochloride
With boron trichloride; tetra-(n-butyl)ammonium iodide In dichloromethane at 0℃; for 7h; Inert atmosphere;81 mg
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
In water at 21℃; for 14h; β-glucosidase, pH 6;
With proteolytic enzymes at 0 - 15℃; Enzymatic reaction;
With recombinant β-glucosidase from Thermotoga maritima In aq. phosphate buffer; dimethyl sulfoxide at 90℃; pH=5.8; Kinetics; Enzymatic reaction;
With glucosidases from Bacillus safensis CGMCC 13129 at 37℃; for 8h; pH=7; Temperature; pH-value; Enzymatic reaction;
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With diphenyldisulfane In tetrahydrofuran Isomerization; Heating;
2-<4-hydroxy-phenyl>-3-<3,5-dihydroxy-phenyl>-acrylic acid

2-<4-hydroxy-phenyl>-3-<3,5-dihydroxy-phenyl>-acrylic acid

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With quinoline; copper at 220℃;
3,5,4'-triacetoxy-trans(?)-stilbene

3,5,4'-triacetoxy-trans(?)-stilbene

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions
ConditionsYield
With sodium hydroxide
With sodium hydroxide
cis-3,4',5-triisopropoxystilbene
587870-59-5

cis-3,4',5-triisopropoxystilbene

A

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

B

cis-resveratrol
61434-67-1

cis-resveratrol

Conditions
ConditionsYield
With boron trichloride In dichloromethane at -78 - 0℃; for 2.25h;
4-Vinylphenol
2628-17-3

4-Vinylphenol

1,3-dihydroxy-5-vinylbenzene
113231-14-4

1,3-dihydroxy-5-vinylbenzene

A

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

B

(E)-3,3',5,5'-tetrahydroxystilbene
33626-09-4

(E)-3,3',5,5'-tetrahydroxystilbene

Conditions
ConditionsYield
Grubbs catalyst first generation In tetrahydrofuran for 1h; Heating;A 95 % Chromat.
B 5 % Chromat.
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

3,5,4'-trimethoxy-trans-stilbene
22255-22-7

3,5,4'-trimethoxy-trans-stilbene

Conditions
ConditionsYield
In methanol; diethyl ether at 10℃; for 24h;100%
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

acetic anhydride
108-24-7

acetic anhydride

triacetyl-trans-resveratrol
42206-94-0

triacetyl-trans-resveratrol

Conditions
ConditionsYield
With pyridine at 20 - 80℃;100%
With sodium hydroxide In dichloromethane; water at 20℃; Concentration; Reagent/catalyst; Solvent; Temperature; Large scale;95%
With triethylamine In dichloromethane at 20℃;92%
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

methyl iodide
74-88-4

methyl iodide

3,5,4'-trimethoxy-trans-stilbene
22255-22-7

3,5,4'-trimethoxy-trans-stilbene

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 20℃; for 2h;100%
Stage #1: (E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol With potassium carbonate In acetone at 25℃; for 0.0833333h; Inert atmosphere;
Stage #2: methyl iodide In acetone at 25℃; for 12h; Inert atmosphere;
93%
Stage #1: (E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol With potassium carbonate In acetone at 25℃; for 0.0833333h; Inert atmosphere;
Stage #2: methyl iodide In acetone at 25℃; for 12h; Inert atmosphere;
93%
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside
3068-32-4

1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside

resveratrol galactoside conjugate peracetate

resveratrol galactoside conjugate peracetate

Conditions
ConditionsYield
With 2,4,6-trimethyl-pyridine; silver carbonate; molecular sieve, 3 A In dichloromethane; acetonitrile at 25℃; for 72h; Under anhydrous N2;100%
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

(E)-3,5,4'-trihydroxy-2,4,6-trideuterostilbene

(E)-3,5,4'-trihydroxy-2,4,6-trideuterostilbene

Conditions
ConditionsYield
With perchloric acid; deuteromethanol at 20℃; for 4h; Reagent/catalyst; Inert atmosphere;100%
With water-d2 In acetonitrile at 90℃; for 24h; Darkness;
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

trans-piceatannol
10083-24-6

trans-piceatannol

Conditions
ConditionsYield
With streptomyces avermilitis tyrosinase; benzene-1,2-diol In aq. buffer for 3h; pH=8; Reagent/catalyst; Enzymatic reaction;100%
With ascorbic acid In aq. phosphate buffer; dimethyl sulfoxide at 30℃; pH=6.0;100%
With benzene-1,2-diol In aq. phosphate buffer at 30℃; pH=7.5; Microbiological reaction; regioselective reaction;
trifluoromethylsulfonic anhydride
358-23-6

trifluoromethylsulfonic anhydride

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

C17H9F9O9S3

C17H9F9O9S3

Conditions
ConditionsYield
With pyridine In dichloromethane at 0 - 20℃;100%
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

piperidine carbamoyl chloride
13939-69-0

piperidine carbamoyl chloride

(E)-3,5,4'-tri[(piperidine-N-carbonyl)oxy]stilbene
1416356-15-4

(E)-3,5,4'-tri[(piperidine-N-carbonyl)oxy]stilbene

Conditions
ConditionsYield
With dmap; potassium carbonate In acetone Reflux; Inert atmosphere;99.3%
4-Nitrophthalonitrile
31643-49-9

4-Nitrophthalonitrile

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

C38H18N6O3

C38H18N6O3

Conditions
ConditionsYield
With potassium carbonate In dimethyl sulfoxide at 80℃; Inert atmosphere;99%
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

n-hexadecanoyl chloride
112-67-4

n-hexadecanoyl chloride

resveratrol tripalmitate
411233-17-5

resveratrol tripalmitate

Conditions
ConditionsYield
With pyridine at 20℃; for 12h;99%
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

carbonochloridic acid, butyl ester
592-34-7

carbonochloridic acid, butyl ester

resveratrol tris(butyl carbonate)

resveratrol tris(butyl carbonate)

Conditions
ConditionsYield
With pyridine In toluene at 20℃;99%
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

dihydroresveratrol
58436-28-5

dihydroresveratrol

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal98%
With 5%-palladium/activated carbon; hydrogen In methanol at 20℃; under 2250.23 Torr; for 3h;97.82%
With palladium 10% on activated carbon; hydrogen In ethanol at 20℃; under 3800.26 Torr; for 8h;95%
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

n-octanoic acid chloride
111-64-8

n-octanoic acid chloride

[4-[(E)-2-[3,5-di(octanoyloxy)phenyl]vinyl]phenyl] octanoate

[4-[(E)-2-[3,5-di(octanoyloxy)phenyl]vinyl]phenyl] octanoate

Conditions
ConditionsYield
Stage #1: (E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol With dmap; triethylamine In dichloromethane at 10℃;
Stage #2: n-octanoic acid chloride In dichloromethane at 10℃; for 1h;
96.7%
With potassium carbonate In acetonitrile at 25℃; for 20h;20%
With pyridine
With pyridine at 20℃;
With potassium carbonate In acetonitrile at 25℃; for 20h;
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

(E)-2,4-dihydroxyl-6-(4′-hydroxylstyryl)benzaldehyde

(E)-2,4-dihydroxyl-6-(4′-hydroxylstyryl)benzaldehyde

Conditions
ConditionsYield
Stage #1: (E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol; N,N-dimethyl-formamide With trichlorophosphate In acetonitrile at 20℃; for 2.5h; Vilsmeier reaction; Cooling with ice;
Stage #2: With water In acetonitrile at 50℃; for 3h; Vilsmeier reaction;
96%
With trichlorophosphate In N,N-dimethyl-formamide; acetonitrile at 20℃; for 2.5h; Vilsmeier Reaction; Cooling with ice;96%
With trichlorophosphate at 20℃; for 3h; Cooling with ice;95%
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

acetic anhydride
108-24-7

acetic anhydride

acetyl-trans-resveratrol

acetyl-trans-resveratrol

Conditions
ConditionsYield
With triethylamine In ethyl acetate at 0 - 70℃; for 2h;96%
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

benzyl bromide
100-39-0

benzyl bromide

(E)-1-(4-(benzyloxy)phenyl)-2-(3,5-bis(benzyloxy)phenyl)-ethene
89946-06-5

(E)-1-(4-(benzyloxy)phenyl)-2-(3,5-bis(benzyloxy)phenyl)-ethene

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 16h;95%
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

potassium hydrogencarbonate
298-14-6

potassium hydrogencarbonate

(E)-2,6-dihydroxy-4-(4-hydroxystyryl)benzoic acid

(E)-2,6-dihydroxy-4-(4-hydroxystyryl)benzoic acid

Conditions
ConditionsYield
With Lyophilized E. coli whole cells overexpressed Rhizobium sp. 2,6-dihydroxybenzoic acid decarboxylase In methanol; aq. phosphate buffer at 30℃; for 24h; pH=8.5; Catalytic behavior; Reagent/catalyst; Solvent; Enzymatic reaction; regioselective reaction;95%
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

2-ethylhexanoic acid chloride
760-67-8

2-ethylhexanoic acid chloride

(E)-5-(4-(2-ethylhexanoyloxy)styryl)-1,3-phenylene bis(2-ethylhexanoate)

(E)-5-(4-(2-ethylhexanoyloxy)styryl)-1,3-phenylene bis(2-ethylhexanoate)

Conditions
ConditionsYield
Stage #1: (E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol With dmap; triethylamine In dichloromethane at 10℃;
Stage #2: 2-ethylhexanoic acid chloride In dichloromethane at 10℃; for 1h;
94.8%
3,3-Dimethylacryloyl chloride
3350-78-5

3,3-Dimethylacryloyl chloride

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

(E)-5-(4-(3-methylbut-2-enoyloxy)styryl)-1,3-phenylene bis(3-methylbut-2-enoate)

(E)-5-(4-(3-methylbut-2-enoyloxy)styryl)-1,3-phenylene bis(3-methylbut-2-enoate)

Conditions
ConditionsYield
Stage #1: (E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol With dmap; triethylamine In dichloromethane at 10℃;
Stage #2: 3,3-Dimethylacryloyl chloride In dichloromethane at 10℃; for 1h;
92.5%
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

trans-δ-viniferin
62218-12-6

trans-δ-viniferin

Conditions
ConditionsYield
With dihydrogen peroxide In water; acetone at 40℃; for 1h; Reagent/catalyst;92%
Stage #1: (E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol With horseradish peroxidase In acetone at 40℃; for 0.5h; pH=8;
Stage #2: With dihydrogen peroxide In acetone at 40℃; for 1h; pH=8;
89%
With silver(I) acetate In methanol at 50℃; for 1h;86%
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

cis-resveratrol
61434-67-1

cis-resveratrol

Conditions
ConditionsYield
for 1.66667h; Irradiation; isomerization;90.6%
Inert atmosphere; UV-irradiation;81%
In ethanol Irradiation;
imidazol-1-ylacetic acid
22884-10-2

imidazol-1-ylacetic acid

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol
501-36-0

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

(E)-3-hydroxy-5-(4-hydroxystyryl)phenyl 2-(1H-imidazol-1-yl)acetate

(E)-3-hydroxy-5-(4-hydroxystyryl)phenyl 2-(1H-imidazol-1-yl)acetate

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane; N,N-dimethyl-formamide at 60℃; for 3h;90%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane; N,N-dimethyl-formamide at 60℃; for 3h;90%

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