4,8,12,16,20-Pentaazatricosanedinitrile, 8,16-bis[3-[bis(2-cyanoethyl)amino]propyl]-4,20-bis(2-cyanoethyl)-12-[2 -(2,5-dihydro-2,5-dioxo-3,4-diphenyl-1H-pyrrol-1-yl)ethyl]-

Base Information

• Chemical Name: 4,8,12,16,20-Pentaazatricosanedinitrile, 8,16-bis[3-[bis(2-cyanoethyl)amino]propyl]-4,20-bis(2-cyanoethyl)-12-[2 -(2,5-dihydro-2,5-dioxo-3,4-diphenyl-1H-pyrrol-1-yl)ethyl]-
• CAS No.: 412008-06-1
• Molecular Formula: C60H82N16O2
• Molecular Weight: 1059.42
• Mol file: 412008-06-1.mol

Synonyms:

Chemical Property of 4,8,12,16,20-Pentaazatricosanedinitrile, 8,16-bis[3-[bis(2-cyanoethyl)amino]propyl]-4,20-bis(2-cyanoethyl)-12-[2 -(2,5-dihydro-2,5-dioxo-3,4-diphenyl-1H-pyrrol-1-yl)ethyl]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,8,12,16,20-Pentaazatricosanedinitrile, 8,16-bis[3-[bis(2-cyanoethyl)amino]propyl]-4,20-bis(2-cyanoethyl)-12-[2 -(2,5-dihydro-2,5-dioxo-3,4-diphenyl-1H-pyrrol-1-yl)ethyl]-

There total 2 articles about 4,8,12,16,20-Pentaazatricosanedinitrile, 8,16-bis[3-[bis(2-cyanoethyl)amino]propyl]-4,20-bis(2-cyanoethyl)-12-[2 -(2,5-dihydro-2,5-dioxo-3,4-diphenyl-1H-pyrrol-1-yl)ethyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2,3-diphenylmaleic anhydride (4808-48-4) + 3-[[3-((3-{(2-amino-ethyl)-[3-(bis-{3-[bis-(2-cyano-ethyl)-amino]-propyl}-amino)-propyl]-amino}-propyl)-{3-[bis-(2-cyano-ethyl)-amino]-propyl}-amino)-propyl]-(2-cyano-ethyl)-amino]-propionitrile (412008-02-7) → 3-[[3-((3-{[3-(bis-{3-[bis-(2-cyano-ethyl)-amino]-propyl}-amino)-propyl]-[2-(2,5-dioxo-3,4-diphenyl-2,5-dihydro-pyrrol-1-yl)-ethyl]-amino}-propyl)-{3-[bis-(2-cyano-ethyl)-amino]-propyl}-amino)-propyl]-(2-cyano-ethyl)-amino]-propionitrile (412008-06-1)

Guidance literature:

In ethanol; at 20 ℃; for 2h;

DOI:10.1016/S0960-894X(01)00618-7

Reference yield:

(2-{bis-[3-(bis-{3-[bis-(2-cyano-ethyl)-amino]-propyl}-amino)-propyl]-amino}-ethyl)-carbamic acid tert-butyl ester (412008-01-6) → 3-[[3-((3-{[3-(bis-{3-[bis-(2-cyano-ethyl)-amino]-propyl}-amino)-propyl]-[2-(2,5-dioxo-3,4-diphenyl-2,5-dihydro-pyrrol-1-yl)-ethyl]-amino}-propyl)-{3-[bis-(2-cyano-ethyl)-amino]-propyl}-amino)-propyl]-(2-cyano-ethyl)-amino]-propionitrile (412008-06-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / TFA / CHCl₃; methoxybenzene / 0.42 h / 0 °C

2: 80 percent / ethanol / 2 h / Heating

With trifluoroacetic acid; In ethanol; chloroform; methoxybenzene;

DOI:10.1016/S0223-5234(02)01362-4

Reference yield: 77.0%

3-[[3-((3-{[3-(bis-{3-[bis-(2-cyano-ethyl)-amino]-propyl}-amino)-propyl]-[2-(2,5-dioxo-3,4-diphenyl-2,5-dihydro-pyrrol-1-yl)-ethyl]-amino}-propyl)-{3-[bis-(2-cyano-ethyl)-amino]-propyl}-amino)-propyl]-(2-cyano-ethyl)-amino]-propionitrile (412008-06-1) → 1-(2-{bis-[3-(bis-{3-[bis-(3-amino-propyl)-amino]-propyl}-amino)-propyl]-amino}-ethyl)-3,4-diphenyl-pyrrole-2,5-dione

Guidance literature:

With sodium hydroxide; hydrogen; Ni-Raney; In ethanol; at 20 ℃; for 16h; under 3102.89 Torr;

DOI:10.1016/S0960-894X(01)00618-7

upstream raw materials:

2,3-diphenylmaleic anhydride

3-[[3-((3-{(2-amino-ethyl)-[3-(bis-{3-[bis-(2-cyano-ethyl)-amino]-propyl}-amino)-propyl]-amino}-propyl)-{3-[bis-(2-cyano-ethyl)-amino]-propyl}-amino)-propyl]-(2-cyano-ethyl)-amino]-propionitrile

(2-{bis-[3-(bis-{3-[bis-(2-cyano-ethyl)-amino]-propyl}-amino)-propyl]-amino}-ethyl)-carbamic acid tert-butyl ester