Tert-butyl 4-(5-bromopyridin-3-yl)piperazine-1-carboxylate

Base Information

Chemical Name:Tert-butyl 4-(5-bromopyridin-3-yl)piperazine-1-carboxylate
CAS No.:412348-60-8
Molecular Formula:C14H20BrN3O2
Molecular Weight:342.236
Hs Code.:
DSSTox Substance ID:DTXSID50470092
Mol file:412348-60-8.mol

Synonyms:Tert-butyl 4-(5-bromopyridin-3-yl)piperazine-1-carboxylate;412348-60-8;1-(5-Bromo-3-pyridyl)-4-tert-butoxycarbonylpiperazine;tert-Butyl4-(5-bromopyridin-3-yl)piperazine-1-carboxylate;SCHEMBL1704960;DTXSID50470092;PBGUMXARVWXJNO-UHFFFAOYSA-N;4-(5-bromopyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester;AKOS016014979;MB10383;WS-01770;FT-0714758;EN300-2916687;A1-18797;J-503406;4-(5-Bromo-pyridin-3-yl)-piperazine-1-carboxylic Acid Tert-Butyl Ester

Suppliers and Price of Tert-butyl 4-(5-bromopyridin-3-yl)piperazine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
tert-Butyl 4-(5-bromopyridin-3-yl)piperazine-1-carboxylate
1g
$ 1143.00

Crysdot
tert-Butyl4-(5-bromopyridin-3-yl)piperazine-1-carboxylate 95+%
1g
$ 412.00

Chemenu
tert-Butyl4-(5-bromopyridin-3-yl)piperazine-1-carboxylate 95%
1g
$ 389.00

American Custom Chemicals Corporation
TERT-BUTYL-4-(5-BROMOPYRIDIN-3-YL)PIPERAZINE-1-CARBOXYLATE 95.00%
5MG
$ 505.02

Alichem
tert-Butyl4-(5-bromopyridin-3-yl)piperazine-1-carboxylate
1g
$ 459.90

Alichem
tert-Butyl4-(5-bromopyridin-3-yl)piperazine-1-carboxylate
250mg
$ 175.00

A1 Biochem Labs
tert-Butyl4-(5-bromopyridin-3-yl)piperazine-1-carboxylate 95%
5 g
$ 1150.00

Total 11 raw suppliers

Chemical Property of Tert-butyl 4-(5-bromopyridin-3-yl)piperazine-1-carboxylate

Chemical Property:

Melting Point:112.9-114.1 °C
Boiling Point:432.9±45.0 °C(Predicted)
PKA:4.61±0.22(Predicted)
PSA：45.67000
Density:1.372±0.06 g/cm3(Predicted)
LogP:2.90410
Storage Temp.:2-8°C
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:341.07389
Heavy Atom Count:20
Complexity:338

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl 4-(5-bromopyridin-3-yl)piperazine-1-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCN(CC1)C2=CC(=CN=C2)Br

Technology Process of Tert-butyl 4-(5-bromopyridin-3-yl)piperazine-1-carboxylate

There total 1 articles about Tert-butyl 4-(5-bromopyridin-3-yl)piperazine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

: 625-92-3
3,5-dibromopyridine

: 224311-51-7
johnphos

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 412348-60-8
4-(5-bromo-pyridin-3-yl)-piperazine-1-carboxylic acid tert-butyl ester

Guidance literature:: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In 1,4-dioxane; ethyl acetate;

Reference yield: 94.0%

: 412348-60-8
4-(5-bromo-pyridin-3-yl)-piperazine-1-carboxylic acid tert-butyl ester

: 144025-03-6
2,4-difluorophenylboronic acid

: 1143577-18-7
tert-butyl 4-[5-(2,4-difluorophenyl)pyridin-3-yl]piperazine-1-carboxylate

Guidance literature:: With sodium carbonate; In water; toluene; at 100 ℃; for 7h;

Reference yield: 90.0%

: 412348-60-8
4-(5-bromo-pyridin-3-yl)-piperazine-1-carboxylic acid tert-butyl ester

: 98-80-6
phenylboronic acid

: 1143577-98-3
4-(5-phenyl-pyridin-3-yl)-piperazine-1-carboxylic acid tert-butyl ester

Guidance literature:: With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; water; for 10h; Heating / reflux;