alpha-(4-Bromophenyl)-alpha-[2-(dimethylamino)ethyl]-3-pyridinemethanol

Base Information

Chemical Name:alpha-(4-Bromophenyl)-alpha-[2-(dimethylamino)ethyl]-3-pyridinemethanol
CAS No.:41910-98-9
Molecular Formula:C₁₆H₁₉BrN₂O
Molecular Weight:335.244
Hs Code.:2933399090
ChEMBL ID:CHEMBL547272
DSSTox Substance ID:DTXSID60512816
Mol file:41910-98-9.mol

Synonyms:41910-98-9;alpha-(4-Bromophenyl)-alpha-[2-(dimethylamino)ethyl]-3-pyridinemethanol;TCMDC-131412;1-(4-bromophenyl)-3-(dimethylamino)-1-pyridin-3-ylpropan-1-ol;a-(4-Bromophenyl)-a-[2-(dimethylamino)ethyl]-3-pyridinemethanol;CHEMBL547272;DTXSID60512816;|A-(4-Bromophenyl)-|A-[2-(dimethylamino)ethyl]-3-pyridinemethanol;AKOS030255305;FT-0663835;?-(4-Bromophenyl)-?-[2-(dimethylamino)ethyl]-3-pyridinemethanol;1-(4-Bromophenyl)-3-(dimethylamino)-1-(pyridin-3-yl)propan-1-ol;alpha -(4-Bromophenyl)- alpha -[2-(dimethylamino)ethyl]-3-pyridinemethanol

Suppliers and Price of alpha-(4-Bromophenyl)-alpha-[2-(dimethylamino)ethyl]-3-pyridinemethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
α-(4-Bromophenyl)-α-[2-(dimethylamino)ethyl]-3-pyridinemethanol
50mg
$ 125.00

Total 5 raw suppliers

Chemical Property of alpha-(4-Bromophenyl)-alpha-[2-(dimethylamino)ethyl]-3-pyridinemethanol

Chemical Property:

Vapor Pressure:1.96E-09mmHg at 25°C
Boiling Point:464.7oC at 760 mmHg
PKA:12.52±0.29(Predicted)
Flash Point:234.8oC
PSA：36.36000
Density:1.341g/cm3
LogP:3.03170
Solubility.:Chloroform, Methanol
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:334.06808
Heavy Atom Count:20
Complexity:292

Purity/Quality:

98%Min ^*data from raw suppliers

α-(4-Bromophenyl)-α-[2-(dimethylamino)ethyl]-3-pyridinemethanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(C)CCC(C1=CC=C(C=C1)Br)(C2=CN=CC=C2)O
Uses Intermediate for the preparation of Zimeldine

Technology Process of alpha-(4-Bromophenyl)-alpha-[2-(dimethylamino)ethyl]-3-pyridinemethanol

There total 2 articles about alpha-(4-Bromophenyl)-alpha-[2-(dimethylamino)ethyl]-3-pyridinemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 626-55-1,163928-56-1
3-Bromopyridine

: 2138-34-3
1-(4-bromo-phenyl)-3-dimethylamino-propan-1-one

: 41910-98-9
1-(4-bromophenyl)-3-(dimethylamino)-1-(3-pyridyl)propan-1-ol

Guidance literature:: With n-butyllithium; In diethyl ether; hexane; 1.) -60 deg C, 1 h, 2.) -40 to -30 deg C, 50 min, 3.) to room temperature, 2.5 h;
DOI:10.3891/acta.chem.scand.36b-0091

Reference yield:

: 41910-98-9
1-(4-bromophenyl)-3-(dimethylamino)-1-(3-pyridyl)propan-1-ol

Guidance literature:: 3-Brom-pyridin, 1.) BuLi/Et2O, 2.) ω-Dimethylamino-4'-brom-propiophenon;

Reference yield:

: 41910-98-9
1-(4-bromophenyl)-3-(dimethylamino)-1-(3-pyridyl)propan-1-ol

: 82103-83-1
(E)-1-(4-bromophenyl)-3-pthalimido-1-(3-pyridyl)propene

Guidance literature:: Multi-step reaction with 3 steps

1: conc. H₂SO₄, Ac₂O / 0.5 h / Heating

2: 57 percent / ClCOOCH₂CCl₃ / benzene / 2 h / Heating

3: 35 percent / dimethylformamide / 3 h / 80 °C

With sulfuric acid; acetic anhydride; 2,2,2-Trichloroethyl chloroformate; In N,N-dimethyl-formamide; benzene;
DOI:10.3891/acta.chem.scand.36b-0091