2-Nitro-4-(trifluoromethyl)benzophenone

Base Information

Chemical Name:2-Nitro-4-(trifluoromethyl)benzophenone
CAS No.:41938-65-2
Molecular Formula:C14H8F3NO3
Molecular Weight:295.218
Hs Code.:
DSSTox Substance ID:DTXSID601227982
Nikkaji Number:J2.104.650G
Mol file:41938-65-2.mol

Synonyms:2-Nitro-4-(trifluoromethyl)benzophenone;SCHEMBL9298819;IJIZUDBTLSSVBO-UHFFFAOYSA-N;DTXSID601227982;41938-65-2;[2-Nitro-4-(trifluoromethyl)phenyl]phenylmethanone;[2-nitro-4-(trifluoromethyl)phenyl]-phenylmethanone;[2-nitro-4-(trifluoromethyl)phenyl](phenyl)methanone

Suppliers and Price of 2-Nitro-4-(trifluoromethyl)benzophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-Nitro-4-(trifluoromethyl)benzophenone

Chemical Property:

XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:295.04562760
Heavy Atom Count:21
Complexity:399

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)C2=C(C=C(C=C2)C(F)(F)F)[N+](=O)[O-]

Technology Process of 2-Nitro-4-(trifluoromethyl)benzophenone

There total 6 articles about 2-Nitro-4-(trifluoromethyl)benzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 781647-92-5
(R)-2-nitro-4-trifluoromethylbenzilic acid

: 41938-65-2
2-nitro-4-trifluoromethylbenzophenone

Guidance literature:: With substituted o-phenylenediamine Co(III); oxygen; pivalaldehyde; In acetonitrile;
DOI:10.1021/jo0402069

Reference yield:

: 367-86-2
1-fluoro-2-nitro-4-trifluoromethyl-benzene

: 41938-65-2
2-nitro-4-trifluoromethylbenzophenone

Guidance literature:: Multi-step reaction with 3 steps

1.1: LDA; HMPA / heptane; tetrahydrofuran; ethylbenzene / 0.5 h / -78 °C

1.2: 80 percent / HMPA / heptane; tetrahydrofuran; ethylbenzene / 0.17 h / -78 °C

2.1: 84 percent / KOH / ethanol / 20 °C

3.1: 84 percent / O₂; pivalaldehyde; substituted o-phenylenediamine Co(III) complex / acetonitrile

With N,N,N,N,N,N-hexamethylphosphoric triamide; potassium hydroxide; substituted o-phenylenediamine Co(III); oxygen; pivalaldehyde; lithium diisopropyl amide; In tetrahydrofuran; ethanol; n-heptane; ethylbenzene; acetonitrile;
DOI:10.1021/jo0402069

Reference yield:

: 81036-97-7
(2S,5S)-2-tert-butyl-5-phenyl-1,3-dioxolan-4-one

: 41938-65-2
2-nitro-4-trifluoromethylbenzophenone

Guidance literature:: Multi-step reaction with 3 steps

1.1: LDA; HMPA / heptane; tetrahydrofuran; ethylbenzene / 0.5 h / -78 °C

1.2: 80 percent / HMPA / heptane; tetrahydrofuran; ethylbenzene / 0.17 h / -78 °C

2.1: 84 percent / KOH / ethanol / 20 °C

3.1: 84 percent / O₂; pivalaldehyde; substituted o-phenylenediamine Co(III) complex / acetonitrile

With N,N,N,N,N,N-hexamethylphosphoric triamide; potassium hydroxide; substituted o-phenylenediamine Co(III); oxygen; pivalaldehyde; lithium diisopropyl amide; In tetrahydrofuran; ethanol; n-heptane; ethylbenzene; acetonitrile;
DOI:10.1021/jo0402069