1,2-Bis(4-hydroxy-3-methoxyphenyl)propane-1,3-diol

Base Information

Chemical Name:1,2-Bis(4-hydroxy-3-methoxyphenyl)propane-1,3-diol
CAS No.:4206-59-1
Molecular Formula:C₁₇H₂₀O₆
Molecular Weight:320.342
Hs Code.:
DSSTox Substance ID:DTXSID30423768
Nikkaji Number:J304.420C
Wikidata:Q27159217
Metabolomics Workbench ID:70732
Mol file:4206-59-1.mol

Synonyms:1,2-diguaiacylpropane-1,3-diol;1,2-bis(4-hydroxy-3-methoxyphenyl)propane-1,3-diol;bmse010100;4206-59-1;1,3-Propanediol, 1,2-bis(4-hydroxy-3-methoxyphenyl)-;AC1O511L;CTK1D3457;SCHEMBL24740779;CHEBI:86530;DTXSID30423768;1,2-Diguaiacyl-1,3-propanediol;DFUOJBWSSSODTR-UHFFFAOYSA-N;1-(4-Hydroxy-3-methoxyphenyl)-1,3-dihydroxy-2-(2-methoxyphenoxy)-propan;1,2-bis(4-hydroxy-3-methoxy-phenyl)propane-1,3-diol;1,2-bis(4-hydroxy-3-methoxyphenyl)-propane-1,3-diol;Q27159217

Suppliers and Price of 1,2-Bis(4-hydroxy-3-methoxyphenyl)propane-1,3-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 11 raw suppliers

Chemical Property of 1,2-Bis(4-hydroxy-3-methoxyphenyl)propane-1,3-diol

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:320.12598835
Heavy Atom Count:23
Complexity:352

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)C(CO)C(C2=CC(=C(C=C2)O)OC)O)O

Technology Process of 1,2-Bis(4-hydroxy-3-methoxyphenyl)propane-1,3-diol

There total 14 articles about 1,2-Bis(4-hydroxy-3-methoxyphenyl)propane-1,3-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 69887-40-7,69887-41-8,115509-61-0,115509-62-1,79171-62-3,4206-59-1
1,2-bis(4-hydroxy-3-methoxyphenyl)propane-1,3-diol

Guidance literature:: /BRN= 343120/ (IX), Hydrierung;
DOI:10.1016/S0040-4039(00)90166-7

Reference yield:

: 2426-87-1
3-methoxy-4-(phenylmethoxy)benzaldehyde

: 4206-59-1,69887-40-7,69887-41-8,79171-62-3,115509-61-0,115509-62-1
erythro-1-phenyl-(4'-hydroxy-3'-methoxy)-2-phenyl-(4-hydroxy-3-methoxy)-1,3-propanediol

Guidance literature:: Multi-step reaction with 4 steps

1: 87 percent / potassium hydroxide / H₂O; ethanol / 2 h

2: 79 percent / 35 percent hydrogen peroxide, 3 M sodium hydroxide, tetrabutylammonium hydrogen sulfate / CH₂Cl₂ / 1.) 0 deg C up to 16 deg C, 6 h

3: 1.) BF₃*(C₂H₅)2O, 2.) sodium borohydride / 1.) ether, reflux, 30 min, 2.) tetrahydrofurane, 52 h

4: hydrogen / 5 percent Pd/C / ethanol

With potassium hydroxide; sodium hydroxide; sodium tetrahydroborate; boron trifluoride diethyl etherate; hydrogen; dihydrogen peroxide; tetra(n-butyl)ammonium hydrogensulfate; palladium on activated charcoal; In ethanol; dichloromethane; water;