tert-butyl [(1R)-1-phenylbut-3-enyl] carbonate

Base Information

Chemical Name:tert-butyl [(1R)-1-phenylbut-3-enyl] carbonate
CAS No.:423763-77-3
Molecular Formula:C15H20O3
Molecular Weight:248.322
Hs Code.:
DSSTox Substance ID:DTXSID40449752
Nikkaji Number:J1.667.288B
Wikidata:Q82269266
Mol file:423763-77-3.mol

Synonyms:CTK1D3245;423763-77-3;DTXSID40449752;Carbonic acid O-tert-butyl O-[(R)-1-phenyl-3-butenyl] ester

Suppliers and Price of tert-butyl [(1R)-1-phenylbut-3-enyl] carbonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of tert-butyl [(1R)-1-phenylbut-3-enyl] carbonate

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:248.14124450
Heavy Atom Count:18
Complexity:272

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)OC(CC=C)C1=CC=CC=C1
Isomeric SMILES:CC(C)(C)OC(=O)O[C@H](CC=C)C1=CC=CC=C1

Technology Process of tert-butyl [(1R)-1-phenylbut-3-enyl] carbonate

There total 6 articles about tert-butyl [(1R)-1-phenylbut-3-enyl] carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 85551-57-1,936-58-3
(R)-1-Phenylbut-3-en-1-ol

: 2-(tert-butoxycarbonyloxyimino)-2-phenylacetonitrile

: 423763-77-3
(1R)-carbonic acid tert-butyl ester 1-phenylbut-3-enyl ester

Guidance literature:: With n-butyllithium; In tetrahydrofuran; diethyl ether; at -78 - 20 ℃; for 2.5h;
DOI:10.1016/S0040-4039(01)02105-0

Reference yield: 90.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 85551-57-1,936-58-3
(R)-1-Phenylbut-3-en-1-ol

: 423763-77-3
(1R)-carbonic acid tert-butyl ester 1-phenylbut-3-enyl ester

Guidance literature:: With dmap; In acetonitrile; for 5h;
DOI:10.1021/jo020501y

Reference yield:

: 6249-80-5
1-phenylbut-3-en-1-one

: 423763-77-3
(1R)-carbonic acid tert-butyl ester 1-phenylbut-3-enyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / (+)-B-chlorodiisopinocampheylborane / tetrahydrofuran / -35 °C

2: 90 percent / 4-(dimethylamino)pyridine / acetonitrile / 5 h

With dmap; (+)-β-chlorodiisopinocampheylborane; In tetrahydrofuran; acetonitrile;
DOI:10.1021/jo020501y