CIS-2-AMINO-CYCLOHEPTANECARBOXYLIC ACID

Base Information

Chemical Name:CIS-2-AMINO-CYCLOHEPTANECARBOXYLIC ACID
CAS No.:42418-83-7
Molecular Formula:C8H15NO2
Molecular Weight:157.21000
Hs Code.:
Mol file:42418-83-7.mol

Synonyms:

Suppliers and Price of CIS-2-AMINO-CYCLOHEPTANECARBOXYLIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Iris Biotech GmbH
cis-2-Aminocycloheptane-COOH*HCl
5 g
$ 1228.50

American Custom Chemicals Corporation
CIS-2-AMINO-CYCLOHEPTANECARBOXYLIC ACID 95.00%
5MG
$ 502.12

Total 7 raw suppliers

Chemical Property of CIS-2-AMINO-CYCLOHEPTANECARBOXYLIC ACID

Chemical Property:

Vapor Pressure:0.000357mmHg at 25°C
Boiling Point:296oC at 760 mmHg
PKA:3.89±0.20(Predicted)
Flash Point:132.8oC
PSA：63.32000
Density:1.091g/cm3
LogP:1.67890

Purity/Quality:

98%Min ^*data from raw suppliers

cis-2-Aminocycloheptane-COOH*HCl ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of CIS-2-AMINO-CYCLOHEPTANECARBOXYLIC ACID

There total 11 articles about CIS-2-AMINO-CYCLOHEPTANECARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: cis-8-azabicyclo[5.2.0]nonan-9-one

: 522644-03-7,42418-83-7
cis-2-Amino-cycloheptancarbonsaeure

: (1S,7R)-8-azabicyclo[5.2.0]nonan-9-one

Guidance literature:: With immobilized lipase B from Candida antarctica; water; In di-isopropyl ether; at 60 ℃; for 31h;
DOI:10.1021/ol034096o

Reference yield:

: 1189-71-5
isocyanate de chlorosulfonyle

: 628-92-2,45509-99-7
Cycloheptene

: 42418-83-7
cis-2-aminocycloheptanecarboxylic acid

Guidance literature:: isocyanate de chlorosulfonyle; Cycloheptene; In dichloromethane; for 10h; Heating / reflux;

With water; In dichloromethane;

With sodium hydroxide; sodium sulfite; In diethyl ether; for 3h; pH=7 - 8;

Reference yield:

: ethyl cis-2-hydroxycycloheptanecarboxylate

: 857633-73-9,42418-83-7
(1R,2R)-2-aminocycloheptanecarboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: pyridine / 14 h / 20 °C

2.1: NaN₃; tetrabutylammonium bromide / dimethylformamide / 16 h / 20 °C

3.1: H₂ / Pd/C / ethyl acetate / 2 h / 20 °C

4.1: aq. HCl / 30 h / 20 °C

4.2: propylene oxide / 2 h / Heating

With pyridine; hydrogenchloride; sodium azide; tetrabutylammomium bromide; hydrogen; palladium on activated charcoal; In ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1055/s-2005-861875