Technology Process of BIPHENYL-3-CARBONYL CHLORIDE
There total 10 articles about BIPHENYL-3-CARBONYL CHLORIDE which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
3-phenylbenzoic acid;
With
N,N-dimethyl-formamide;
In
dichloromethane;
at 0 ℃;
for 0.0833333h;
With
oxalyl dichloride;
In
dichloromethane;
at 20 ℃;
for 12h;
DOI:10.1021/jacs.0c13415
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium phosphate tribasic trihydrate; tetrakis(triphenylphosphine) palladium(0) / 1,4-dioxane / 7 h / 90 °C / Inert atmosphere
2: sodium hydroxide / water; methanol / 2 h / Reflux
3: thionyl chloride / 1.5 h / Reflux
With
tetrakis(triphenylphosphine) palladium(0); thionyl chloride; potassium phosphate tribasic trihydrate; sodium hydroxide;
In
1,4-dioxane; methanol; water;
DOI:10.1039/c3dt50834j
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) n-BuLi, 2.) ZnCl2, 3.) DIBAL-H, Ni(PPh3)2l2
2: 79.5 percent / 1 N NaOH / ethanol / 18 h / Ambient temperature
3: (COCl)2 / CH2Cl2; dimethylformamide / 1 h
With
sodium hydroxide; n-butyllithium; oxalyl dichloride; bis(triphenylphosphine)nickel(II) diiodide; diisobutylaluminium hydride; zinc(II) chloride;
In
ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1248/cpb.45.1870
