Methyl 2-[2-(2-benzamidoethyl)-1,3-thiazol-4-yl]-1,3-thiazole-4-carboxylate

Base Information

Chemical Name:Methyl 2-[2-(2-benzamidoethyl)-1,3-thiazol-4-yl]-1,3-thiazole-4-carboxylate
CAS No.:76275-90-6
Molecular Formula:C17H15N3O3S2
Molecular Weight:373.456
Hs Code.:
NSC Number:359285
DSSTox Substance ID:DTXSID40320431
Wikidata:Q82077555

Synonyms:76275-90-6;NSC 359285;NSC359285;DTXSID40320431;NSC-359285;methyl 2-[2-(2-benzamidoethyl)-1,3-thiazol-4-yl]-1,3-thiazole-4-carboxylate

Suppliers and Price of Methyl 2-[2-(2-benzamidoethyl)-1,3-thiazol-4-yl]-1,3-thiazole-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Methyl 2-[2-(2-benzamidoethyl)-1,3-thiazol-4-yl]-1,3-thiazole-4-carboxylate

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:7
Exact Mass:373.05548370
Heavy Atom Count:25
Complexity:474

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=CSC(=N1)C2=CSC(=N2)CCNC(=O)C3=CC=CC=C3

Technology Process of Methyl 2-[2-(2-benzamidoethyl)-1,3-thiazol-4-yl]-1,3-thiazole-4-carboxylate

There total 3 articles about Methyl 2-[2-(2-benzamidoethyl)-1,3-thiazol-4-yl]-1,3-thiazole-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 76275-87-1
methyl 2-acetylthiazole-4-carboxylate

: 76275-90-6
methyl 2'-(2-benzamidomethyl)-2,4'-bithiazole-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: Br₂, AcOH

2: ethanol / 15 h / 70 °C

With bromine; acetic acid; In ethanol;
DOI:10.1021/ja00092a011

Reference yield:

: 30761-30-9
β-benzamidothiopropionamide

: 76275-88-2
2-(2-bromo-acetyl)-thiazole-4-carboxylic acid methyl ester

: 76275-90-6
methyl 2'-(2-benzamidomethyl)-2,4'-bithiazole-4-carboxylate

Guidance literature:: In ethanol; at 70 ℃; for 15h; Yield given;
DOI:10.1021/ja00092a011

Reference yield:

: 76275-86-0
(+/-)-4-methoxycarbonyl-2-(1-hydroxyethyl)thiazole

: 76275-90-6
methyl 2'-(2-benzamidomethyl)-2,4'-bithiazole-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / manganese dioxide / CH₂Cl₂ / 3 h / Heating

2: 1.) acetic acid, Br₂ / 2.) DMF, 70 deg C, 1.5 h

With manganese(IV) oxide; bromine; acetic acid; In dichloromethane;
DOI:10.1021/jm00135a008