76275-86-0 Usage
Uses
Used in Pharmaceutical Industry:
(+/-)-4-methoxycarbonyl-2-(1-hydroxyethyl)thiazole is used as a pharmaceutical agent for its potential antimicrobial, antifungal, and anticancer properties. Thiazole derivatives are known for their diverse pharmacological activities, making (+/-)-4-methoxycarbonyl-2-(1-hydroxyethyl)thiazole a candidate for further research and development in creating new drugs and therapeutic agents.
Used in Drug Development:
(+/-)-4-methoxycarbonyl-2-(1-hydroxyethyl)thiazole is utilized in the development of pharmaceutical agents with improved solubility and bioavailability. The presence of the hydroxyethyl group suggests that (+/-)-4-methoxycarbonyl-2-(1-hydroxyethyl)thiazole could be instrumental in creating drugs that are more easily absorbed and effective in the body, thus enhancing their therapeutic potential.
Check Digit Verification of cas no
The CAS Registry Mumber 76275-86-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,2,7 and 5 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 76275-86:
(7*7)+(6*6)+(5*2)+(4*7)+(3*5)+(2*8)+(1*6)=160
160 % 10 = 0
So 76275-86-0 is a valid CAS Registry Number.
76275-86-0Relevant academic research and scientific papers
Total synthesis of myxothiazols, novel bis-thiazole β-methoxyacrylate- based anti-fungal compounds from myxobacteria
Clough, John M.,Dube, Henry,Martin, Bruce J.,Pattenden, Gerald,Reddy, K. Srinivasa,Waldron, Ian R.
, p. 2906 - 2911 (2008/02/09)
Convergent total syntheses of myxothiazols A and Z are described. The syntheses are based on elaboration of the (S)-E,E-diene thioamide 22, conversion of 22 into the bis-thiazole 27 and Wittig reactions between 27c and the aldehyde 30. The substituted β-m
Synthesis of ozonolysis products of myxothiazol
Akita,Nozawa,Nagumo
, p. 1208 - 1212 (2007/10/02)
By applying the Hantzsch thiazole procedure, the synthesis of bithiazole derivatives (2 and (±)-3) corresponding to degradation products of myxothiazol was achieved. Optically active (S)-3 (87-88% ee) and its analog (S)-16 (91% ee) were obtained through enantioselective hydrolysis of the corresponding acetates ((±)-18, (±)-20 and (±)-21) using lipase in water- saturated organic solvent.
